Acetazolamide
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Acute kidney dysfunction: case report A 47-year-old woman developed acute kidney dysfunction during treatment with acetazolamide for idiopathic intracranial hypertension. The woman, who was a live-kidney donor, presented with a 6 month history of headaches and a weeks history of blurred vision. Examinations showed an inferior nasal field defect and grade 2 papilledema in both eyes. She also showed severely stenosed dominant right sided venous sinus draining into right jugular bulb and aplastic left transverse sinus. Lumbar puncture demonstrated opening pressure of 40cm H2O with normal CSF composition. She was diagnosed with idiopathic intracranial hypertension and started receiving acetazolamide 500mg twice daily [route not stated]. However, she developed acute kidney dysfunction [time to reaction onset and outcome not stated]. The woman’s acetazolamide was discontinued. Later, she received a 5-day dual antiplatelet therapy along with aspirin and clopidogrel, and underwent venous sinus stenting. Subsequently, she underwent balloon angioplasty, resulting in resolved stenosis and pressure gradient, along with improvement in the flow through occipital sinus. The bilateral papilledema resolved along with stable right eye inferior nasal defect. A normal CSF opening pressure was noted. Al Balushi A, et al. Idiopathic intracranial hypertension with stenosis of a solitary occipital venous sinus treated with stenting. Interventional Neuroradiology 26: 664-667, No. 803517796 5, Oct 2020. Available from: URL: http://doi.org/10.1177/1591019920949094
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Reactions 28 Nov 2020 No. 1832
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