Adenotonsillectomy outcomes regarding bone age and osteocalcin in treatment of obstructive sleep apnea syndrome in child
- PDF / 289,300 Bytes
- 7 Pages / 595.22 x 842 pts (A4) Page_size
- 90 Downloads / 171 Views
Adenotonsillectomy outcomes regarding bone age and osteocalcin in treatment of obstructive sleep apnea syndrome in children Qing-Biao Zhang, Yin-Feng Li, Ming-Xiu Li, Ling-Yu Kong, Liang-Fu Jiang, Hui-Wei Feng, Xian-Liang Fan Linyi, China
Methods: Preoperative and postoperative (6 months) physical examination, PSG, bone age (BA) and osteocalcin (OC) evaluation were performed on the selected OSA children (n=92) and the healthy children (n=87). The OSA children were also scored based on the OSA 18-item questionnaire. A two-year follow-up was conducted to evaluate BA and OC changes. Results: After AT, 81 (88.04%) OSA children recovered completely, eight (8.70%) achieved remarkable improvements, and three (3.26%) achieved moderate improvements. In the OSA children, postoperative OSA 18-item score and the scores of the five domains were significantly higher than preoperative ones. Compared with the preoperative, body mass index (BMI), weight for age Z-sores, height for age Z-sores, weight for height Z-sores and BMI Z-score in the OSA group 6 months after the operation were significantly increased, but no significant difference was detected between the OSA and the control group. The changes of BA and chronological age in the OSA group were significantly different from those in the control group. Two years after AT, BA between the two groups was no longer significantly different. Preoperative serum OC in the OSA group was
Author Affiliations: Department of Pediatric Internal Medicine, Linyi People's Hospital, Linyi, China (Zhang QB, Li YF, Feng HW, Fan XL); Department of Pediatric Surgery, Linyi People's Hospital, Linyi, China (Li MX, Jiang LF); Department of Breast Surgery, Linyi Cancer Hospital, Linyi, China (Kong LY) Corresponding Author: Ming-Xiu Li, Department of Pediatric Surgery, Linyi People's Hospital, No.27 East Jiefang Road, Linyi 276003, China (Tel: +86-0539-8078008; Email: [email protected]) doi: 10.1007/s12519-016-0073-3 ©Children's Hospital, Zhejiang University School of Medicine, China and Springer-Verlag Berlin Heidelberg 2016. All rights reserved.
World J Pediatr, Online First, November 2016 . www.wjpch.com
lower than that in the control group, but increased to normal levels 6 months after AT. Correlation analysis showed serum OC levels were negatively correlated with apnea hyponea index, obstructive apnea index, arousal index, and lowest oxygen saturation. Conclusions: After AT, bone growth and development in children with OSA recovered gradually, and the serum OC levels decreased to the normal level. Therefore, preventive measures and positive treatments should be applied to minimize the negative effects of OSA in children. World J Pediatr November 2016; Online First Key words: obstructive sleep apnea syndrome; OSA-18 score; osteocalcin; polysomnography
Introduction
T
he obstructive sleep apnea syndrome (OSA) is a condition characterized by the occurrence of various types of respiratory issues during sleep involving partial occlusion in or complete cessation of the airflow.[1] OSA happens as
Data Loading...
