Association between temporal muscle thickness and clinical outcomes in patients with newly diagnosed glioblastoma

  • PDF / 789,062 Bytes
  • 9 Pages / 595.276 x 790.866 pts Page_size
  • 70 Downloads / 197 Views

DOWNLOAD

REPORT


ORIGINAL ARTICLE – CLINICAL ONCOLOGY

Association between temporal muscle thickness and clinical outcomes in patients with newly diagnosed glioblastoma Geon An1 · Stephen Ahn1   · Jae‑Sung Park1 · Sin‑ Soo Jeun1 · Yong‑ Kil Hong1 Received: 20 July 2020 / Accepted: 4 September 2020 © Springer-Verlag GmbH Germany, part of Springer Nature 2020

Abstract Purpose  Temporal muscle thickness (TMT) has been suggested as a novel biomarker that can represent sarcopenia in head and neck malignancies. This study investigated the association of TMT with clinical outcomes in patients with newly diagnosed glioblastoma (GBM). Methods  Using electronic medical records, all GBM patients between 2008 and 2018 at Seoul St. Mary’s Hospital were reviewed. Total 177 patients met our eligibility criteria. Results  The thinner group who had TMT less than the median showed shorter overall survival (OS) and progression-free survival (PFS) than the thicker group who had TMT more than median (OS; 11.0 versus 18.0 months, p