Automation in Hematology What to Measure and Why?
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With 106 Figures and 45 Tables
Springer-Verlag Berlin Heidelberg GmbH 1981
Acknowledgements This Symposium, held at the Institut de Pathologie Cellulaire, (INSERM 48) Höpital de Bid~tre, France, July 15-17, 1979 was made possible by the generosity of Abbott Laboratories, Becton-Dickinson, Coulter Electronics, Geometrie Data, Ortho Instruments and Technicon Instruments Corp. Dennis Ross, University of North Carolina, School of Medicine, Chapel Hili, NC 27514, USA George BRECHER, University of California, Donner Laboratory, Berkeley, CA 94720, USA Marcel BEssis, Institut de Pathologie Cellulaire, Höpital de Bicetre, 94270 Bicetre, France
This monograph comprises Vol. 6, 2-3 of the international journal Blood Cells (Editor: Marcel Bessis, Assistant Editors: N. Mohandas and D.W. Ross) ISBN 978-3-642-67756-4 (eBook) ISBN 978-3-540-10225-0 DOI 10.1007/978-3-642-67756-4 This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically those of translation, reprinting, re-use of illustrations, broadcastings, reproduction by photocopying machine or similar means, and storage in data banks. Under §54 of the German Copyright Law, where copies are made for other than private use, fee is payable to the publisher, the amount of the fee tobe determined by agreement with the publisher. © by Springer-Verlag Berlin Beideiberg 1981.
The use of general descriptive names, trade names, trade marks etc. in this publication, even if the former are not especially identified, is not be taken as a sign that such names, as understood by the Trade Marks and Merchandise Marks Act, may accordingly be used freely by anyone.
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Table of Contents INTRODUCTION
M. WINTROBE: To Measure or not to Measure? That Too Is a Question.
3
G. BRECHER: The Future of Automation in Hematology.
7
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Jean BERNARD, M. BEssis: The Impact of Automation on the Future of Hematology . . . . . . . . . . . . . . . . . . . . .
11
SECTION 1: BIOPHYSICAL PRINCIPLES OF MEASUREMENTS
L.A. KAMENTSKY: Objective Measures of Information From Blood Cells . Discussion . . . . . . . . . . . . . . . . . . .
17 32
W. GRONER, D. TYcKo: Characterizing Blood Cells by Biophysical Measurements in Flow Discussion . . . . . . . . . . . . . . . . . . .
37 51
F. MEYER: Quantitative Analysis of the Chromatin of Lymphocytes: An Essay on Comparative Structuralism . . . . Discussion . . . . . . . . . . . . . .
55 67
M.J. FuLWYLER: Flow Cytometry and Cell Sorting . Discussion . . . . . . . . . . . . . .
69 79
R.S. GALEN: Predictive Value and Efficiency of Hematology Data . Discussion . . . . . . . . . . . . . . . . . . . .
81 92
SECTION 11: PLATELETS
J .L. HAYNES: High Resolution Partiele Analysis- Its Application to Platelet Counting and Suggestions for Further Application in Blood Cell Analysis
97
J.M. PAuLUs, J.F. DESCHAMPS, M. PRENANT, F.J. CASALS: Kinetics of Platelets, Megakaryocytes, and Their Precursors: What to Measure? . 111 Discussion of papers by J.L. Haynes and J.M. Paulus
