Bioinformatics Research and Applications 6th International Sympo

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Edited by S. Istrail, P. Pevzner, and M. Waterman Editorial Board: A. Apostolico S. Brunak M. Gelfand T. Lengauer S. Miyano G. Myers M.-F. Sagot D. Sankoff R. Shamir T. Speed M. Vingron W. Wong

Subseries of Lecture Notes in Computer Science

Mark Borodovsky Johann Peter Gogarten Teresa M. Przytycka Sanguthevar Rajasekaran (Eds.)

Bioinformatics Research and Applications 6th International Symposium, ISBRA 2010 Storrs, CT, USA, May 23-26, 2010 Proceedings

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Series Editors Sorin Istrail, Brown University, Providence, RI, USA Pavel Pevzner, University of California, San Diego, CA, USA Michael Waterman, University of Southern California, Los Angeles, CA, USA Volume Editors Mark Borodovsky Georgia Institute of Technology School of Biology Atlanta, Georgia, USA E-mail: [email protected] Johann Peter Gogarten University of Connecticut Molecular and Cell Biology Department Storrs, CT, USA E-mail: [email protected] Teresa M. Przytycka National Center for Biotechnology Information National Library of Medicine National Institutes of Health Bethesda, MD, USA E-mail: [email protected] Sanguthevar Rajasekaran University of Connecticut Department of Computer Science and Engineering Storrs, CT, USA E-mail: [email protected]

Library of Congress Control Number: Applied for CR Subject Classification (1998): H.3, J.3, H.2.8, H.4, F.1, I.5 LNCS Sublibrary: SL 8 – Bioinformatics ISSN ISBN-10 ISBN-13

0302-9743 3-642-13077-1 Springer Berlin Heidelberg New York 978-3-642-13077-9 Springer Berlin Heidelberg New York

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Preface

The 6th International Symposium on Bioinformatics Research and Applications (ISBRA 2010) was held during May 23–26, 2010 at the University of Connecticut, Storrs, Connecticut. The symposium provided a forum for the exchange of new results and ideas among researchers, developers, and practitioners working on all aspects of bioinformatics, computational biology, and their applications. The program of the symposium included 20 contributed papers selected by the Program Committee from 57 submissions received in response to the call for papers. The symposium also included poster presentations and featured invited keynote talks by six distinguished speakers: Catalin Barbacioru from Life Technologie