Blood pressure levels and cardiovascular risk according to age in patients with diabetes mellitus: a nationwide populati
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ORIGINAL INVESTIGATION
Cardiovascular Diabetology Open Access
Blood pressure levels and cardiovascular risk according to age in patients with diabetes mellitus: a nationwide population‑based cohort study Hack‑Lyoung Kim1†, Hyue Mee Kim2†, Chang Hee Kwon3, Jeong‑Hun Shin4, Mi‑Hyang Jung5, Chan Joo Lee6, Dae‑Hee Kim7, Woo‑Hyeun Kim8, Si‑Hyuck Kang9, Ju‑Hee Lee10, In Jeong Cho11, Iksung Cho6, Jun Hyeok Lee12, Dae Ryong Kang12, Hae‑Young Lee13, Wook‑Jin Chung14, Sang‑Hyun Ihm15, Kwang Il Kim9, Eun Joo Cho16, Il‑Suk Sohn17, Hyeon‑Chang Kim6, Jinho Shin4, Ju Han Kim18, Sung Kee Ryu19, Seok‑Min Kang6, Wook Bum Pyun11, Myeong‑Chan Cho10, Sungha Park6* and Ki‑Chul Sung20*
Abstract Background: Little is known about age-specific target blood pressure (BP) in hypertensive patients with diabetes mellitus (DM). The aim of this study was to determine the BP level at the lowest cardiovascular risk of hypertensive patients with DM according to age. Methods: Using the Korean National Health Insurance Service database, we analyzed patients without cardiovascu‑ lar disease diagnosed with both hypertension and DM from January 2002 to December 2011. Primary end-point was composite cardiovascular events including cardiovascular death, myocardial infarction and stroke. Results: Of 241,148 study patients, 35,396 had cardiovascular events during a median follow-up period of 10 years. At the age of
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