Branched Chain Amino Acids in Clinical Nutrition Volume 2

This is the second volume in a 2-volume compendium that is the go-to source for both research- and practice-oriented information on the importance of branched chain amino acids in maintaining the nutritional status and overall health of individuals, espec

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Rajkumar Rajendram Victor R. Preedy Vinood B. Patel Editors

Branched Chain Amino Acids in Clinical Nutrition Volume 2

NUTRITION AND HEALTH Adrianne Bendich, Ph.D., FASN, FACN, SERIES EDITOR

More information about this series at http://www.springer.com/series/7659

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Rajkumar Rajendram Victor R. Preedy • Vinood B. Patel Editors

Branched Chain Amino Acids in Clinical Nutrition Volume 2

Editors Rajkumar Rajendram Intensive Care Barnet and Chase Farm Hospitals, Royal Free London NHS Foundation Trust London, United Kingdom

Victor R. Preedy Diabetes and Nutritional Sciences Kings College London London, United Kingdom

Vinood B. Patel Department of Biomedical Sciences University of Westminster London, United Kingdom

ISBN 978-1-4939-1913-0 ISBN 978-1-4939-1914-7 (eBook) DOI 10.1007/978-1-4939-1914-7 Springer New York Heidelberg Dordrecht London Library of Congress Control Number: 2014952897 © Springer Science+Business Media New York 2015 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. Exempted from this legal reservation are brief excerpts in connection with reviews or scholarly analysis or material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Duplication of this publication or parts thereof is permitted only under the provisions of the Copyright Law of the Publisher’s location, in its current version, and permission for use must always be obtained from Springer. Permissions for use may be obtained through RightsLink at the Copyright Clearance Center. Violations are liable to prosecution under the respective Copyright Law. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. While the advice and information in this book are believed to be true and accurate at the date of publication, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Humana Press is a brand of Springer Springer is part of Springer Science+Business Media (www.springer.com)

Preface

In man, the branched chain amino acids (leucine, isoleucine, and valine) are essential amino acids and thus must be obtained from dietary components. The branched chain amino acids are not only necessary for the synthe