Cardiac Drugs in Pregnancy

In the western world, the risk of cardiovascular disease in pregnancy has grown due to the increasing age at the first pregnancy and the worldwide obesity epidemic leading to early diabetes and hypertension. As a result more women are requiring drug thera

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Karen Sliwa John Anthony Editors

Cardiac Drugs in Pregnancy

Current Cardiovascular Therapy Series Editor Juan Carlos Kaski

Karen Sliwa • John Anthony Editors

Cardiac Drugs in Pregnancy

Editors Karen Sliwa Department of Medicine, Faculty of Health Sciences Hatter Institute for Cardiovascular Research in Africa Cape Town Western Cape South Africa

John Anthony Department of Obstetrics and Gynaecology Groote Schuur Hospital Cape Town South Africa

ISBN 978-1-4471-5471-6 ISBN 978-1-4471-5472-3 (eBook) DOI 10.1007/978-1-4471-5472-3 Springer London Heidelberg New York Dordrecht Library of Congress Control Number: 2013954833 © Springer-Verlag London 2014 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. Exempted from this legal reservation are brief excerpts in connection with reviews or scholarly analysis or material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Duplication of this publication or parts thereof is permitted only under the provisions of the Copyright Law of the Publisher's location, in its current version, and permission for use must always be obtained from Springer. Permissions for use may be obtained through RightsLink at the Copyright Clearance Center. Violations are liable to prosecution under the respective Copyright Law. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. While the advice and information in this book are believed to be true and accurate at the date of publication, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)

Preface

The spectrum of cardiovascular disease affecting women in pregnancy and postpartum is changing and differs between countries. In the western world, the risk of cardiovascular disease in pregnancy has increased due to the increasing age at the first pregnancy and the worldwide obesity epidemic leading also to early diabetes and hypertension. In addition, the treatment of congenital heart disease has improved leading to an increased number of women with residual heart disease reaching childbearing age. In the western world maternal heart disease is now the ma