Central Nervous System Metastasis, the Biological Basis and Clinical Considerations
This volume covers what is known regarding the natural history, basic biology, and clinical aspects, including imaging and treatment, of CNS metastasis. Three chapters cover the biology of the brain and brain metastases: molecular biology, includes what i
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Cancer Metastasis – Biology and Treatment VOLUME 18 Series Editors Richard J. Ablin, Ph.D., University of Arizona, College of Medicine and The Arizona Cancer Center, AZ, U.S.A. Wen G. Jiang, M.D., F.S.B., Institute of Cancer and Genetics, Cardiff University School of Medicine, Cardiff, U.K. Advisory Editorial Board Harold F. Dvorak, M.D. Phil Gold, M.D., Ph.D. Danny Welch, Ph.D. Hiroshi Kobayashi, M.D., Ph.D. Robert E. Mansel, M.S., FRCS. Klaus Pantel, Ph.D. Recent Volumes in this Series Volume 9: Cell Adhesion and Cytoskeletal Molecules in Metastasis Editors: Anne E. Cress and Raymond B. Nagle ISBN 978-1-4020-5128-X Volume 10: Metastasis of Prostate Cancer Editors: Richard J. Ablin and Malcolm D. Mason ISBN 978-1-4020-5846-2 Volume 11: Metastasis of Breast Cancer Editors: Robert E. Mansel, Oystein Fodstad and Wen G. Jiang ISBN 978-1-4020-5866-7 Volume 12: Bone Metastases: A Translational and Clinical Approach Editors: Dimitrios Kardamakis, Vassilios Vassiliou and Edward Chow ISBN 978-1-4020-9818-5 Volume 13: Lymphangiogenesis in Cancer Metastasis Editors: Steven A. Stacker and Marc G. Achen ISBN 978-90-481-2246-2 Volume 14: Metastasis of Colorectal Cancer Editors: Nicole Beauchemin and Jacques Huot ISBN 978-90-481-8832-1 Volume 15: Signal Transduction in Cancer Metastasis Editors: Wen-Sheng Wu and Chi-Tan Hu ISBN 978-90-481-9521-3 Volume 16: Liver Metastasis: Biology and Clinical Management Editor: Pnina Brodt ISBN 978-94-007-0291-2 Volume 17: Electric Cell-Substrate Impedance Sensing and Cancer Metastasis Editor: Wen G. Jiang ISBN 978-94-007-4926-9
For further volumes: http://www.springer.com/series/5761
Diane Palmieri Editor
Central Nervous System Metastasis, the Biological Basis and Clinical Considerations
Editor Diane Palmieri National Cancer Institute National Institutes of Health Bethesda, MD, USA
ISSN 1568-2102 ISBN 978-94-007-5290-0 ISBN 978-94-007-5291-7 (eBook) DOI 10.1007/978-94-007-5291-7 Springer Dordrecht Heidelberg New York London Library of Congress Control Number: 2012955245 © Springer Science+Business Media Dordrecht 2012 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. Exempted from this legal reservation are brief excerpts in connection with reviews or scholarly analysis or material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Duplication of this publication or parts thereof is permitted only under the provisions of the Copyright Law of the Publisher’s location, in its current version, and permission for use must always be obtained from Springer. Permissions for use may be obtained through
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