Correction to: Regional [ 18 F]flortaucipir PET is more closely associated with disease severity than CSF p-tau in Alzhe
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CORRECTION
Correction to: Regional [18F]flortaucipir PET is more closely associated with disease severity than CSF p-tau in Alzheimer’s disease Emma E. Wolters 1,2 & Rik Ossenkoppele 2,3 & Sander C. J. Verfaillie 1 & Emma M. Coomans 1 & Tessa Timmers 1,2 & Denise Visser 1,2 & Hayel Tuncel 1 & Sandeep S. V. Golla 1 & Albert D. Windhorst 1 & Ronald Boellaard 1 & Wiesje M. van der Flier 2,4 & Charlotte E. Teunissen 5 & Philip Scheltens 2 & Bart N. M. van Berckel 1
# Springer-Verlag GmbH Germany, part of Springer Nature 2020
Correction to: Eur J Nucl Med Mol Imaging https://doi.org/10.1007/s00259-020-04758-2 The authors regret to inform readers that the following error was detected in the original article. The values for entorhinal, limbic and neortical SUVr were switched between SCD Aβ + and Aβ- in Table 1 and have now been corrected. Unnecessary symbols in Table 2 have been removed.
This article is part of the Topical Collection on Erratum. The online version of the original article can be found at https://doi.org/ 10.1007/s00259-020-04758-2 * Emma E. Wolters [email protected] 1
Department of Radiology and Nuclear Medicine, Amsterdam, Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands
2
Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands
3
Clinical Memory Research Unit, Lund University, Lund, Sweden
4
Department of Epidemiology and Biostatistics, Vrije Universiteit, Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands
5
Neurochemistry Laboratory, Department of Clinical Chemistry, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands
Eur J Nucl Med Mol Imaging Table 1 Demographic, clinical and AD biomarker characteristics over the total sample and per disease group
SCD Aβ+
SCD Aβ-
MCI/AD
(n = 15)
(n = 53)
(n = 10) Age, years Female, % No. Aß positive subjects Education, Verhage scale, median(range) Time lag LP/PET, years Neuropsychological measures MMSE (n = 78) Memoryc (n = 78) Attentiond (n = 73) Languagee (n = 68) Executive functioningf (n = 73) Tau biomarkers CSF CSF Aß1–42 CSF t-tau CSF p-tau [18F]flortaucipir PET Entorhinal cortex BPND Limbic region BPND Neocortex BPND Entorhinal cortex SUVr Limbic region SUVr Neocortex SUVr
Total Sample
Total SCD
(n = 78)
(n = 25)
67 ± 6 60% 10(100%) 6 (4–7)
64 ± 6 60% 0(0%) 6 (2–7)
65 ± 7 53% 53 (100%) 6 (3–7)
65 ± 7 43% 63 (81%) 6 (2–7)
65 ± 6 60% 10 (40%) 6 (2–7)
0.7 ± 0.6
0.9 ± 0.5
0.6 ± 0.5
0.7 ± 0.5
0.8 ± 0.7
28 ± 1 −0.5 ± 0.8 −0.2 ± 0.6 −0.0 ± 0.4 −0.1 ± 0.9
28 ± 1 0.3 ± 0.6 0.1 ± 0.6 0.0 ± 0.8 −0.1 ± 0.7
23 ± 4b −3.1 ± 2.1b −1.3 ± 1.2b −1.0 ± 1.0b −2.4 ± 1.0b
25 ± 4 −2.1 ± 2.3 −0.9 ± 1.2 −0.6 ± 1.0 −0.9 ± 1.1
28 ± 1 −0.0 ± 0.8 −0.0 ± 0.6 −0.0 ± 0.7 0.0 ± 0.8
779 ± 197 615 ± 383 83 ± 36
1067 ± 217 257 ± 201 43 ± 23
541 ± 113b 760 ± 412b 90 ± 35b
677 ± 260 645 ± 422 80 ± 38
966 ± 247 401 ± 333 59 ± 38
0.2 ± 0.2 0.2 ± 0.1 0.1 ± 0.1 1.3 ± 0.2 1.3 ± 0.2 1.2 ± 0.2
−0.1 ± 0.
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