Curative Effects of Two New Endometrial Ablation Procedures Using Radiofrequency Thermocoagulation for the Treatment of
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ORIGINAL PAPER
Curative Effects of Two New Endometrial Ablation Procedures Using Radiofrequency Thermocoagulation for the Treatment of Severe Abnormal Uterine Bleeding Geping Yin • Juan Li • Tongyu Zhu Ming Chen
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Published online: 17 January 2013 Ó Springer Science+Business Media New York 2013
Abstract Severe Abnormal Uterine Bleeding (SAUB) is a common gynecological disorder. The clinical characteristics include disordered menstrual cycle and massive bleeding that can cause anemia or secondary infection. Current treatment mainly relies on drug therapy or surgical removal of the uterus, each having its significant disadvantages. How to preserve the uterus, reduce the pain from surgery, and achieve better treatment effects have been well known but remaining as unresolved issues. This study aims at evaluating two types of radiofrequency (RF) thermocoagulation procedures for the treatment of SAUB: the RF-A procedure group included 25 SAUB patients C45 years of age treated for amenorrhea; the RF-B procedure group included 51 patients at \45 years of age treated for the control of excessive bleeding. Post-treatment ratings of menstrual satisfaction and pre-/post-treatment menstrual scores—pictorial blood loss assessment chart (PBAC)—and hemoglobin levels were collected; and the mean length of follow-up was 72 months. Also, 38 SAUB patients treated with standard drug regimens served as a control group. The results of the study showed that following RF treatment, the average long-term patient menstrual satisfaction was greater than 92 %. In both the RF groups, PBAC scores and hemoglobin levels were significantly improved from baseline (p \ .05). Compared with the control group, PBAC scores and hemoglobin levels were also significantly better for the RF groups at 6–24month post-operation. Patients experienced no hysterectomy in association with the RF procedures. In conclusion, this pilot study suggests that the novel RF procedures are G. Yin (&) J. Li T. Zhu M. Chen Department of Obstetrics and Gynecology, Jinan Military General Hospital, #25 Shifan Road, Jinan 250031, China e-mail: [email protected]
both safe and effective in treating patients with SAUB. Further investigation is necessary to evaluate their application in broader clinical indication. Keywords Abnormal uterine bleeding Radiofrequency ablation Minimally-invasive techniques
Introduction The anovulatory abnormal uterine bleeding (AUB) is a common gynecological disorder, occurring in about 10 % of women [1, 2]. Clinical characteristics of AUB include disordered menstrual cycle and massive bleeding that can cause varying degrees of anemia or secondary infection in severe cases. Currently, treatment mainly relies on drug therapy or surgical removal of the uterus [3, 4], each having its significant disadvantages. How to preserve the uterus, reduce the pain from surgery, and achieve better treatment effects remain as yet unresolved issues [5, 6]. The aim of this study is to determine whether Radiofrequency (RF) procedures are safe and effective i
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