Current Aspects of Flavonoids: Their Role in Cancer Treatment

The book comprehensively introduces readers to various aspects of flavonoids, a category of natural metabolites that exhibits various pharmacological effects. It discusses their chemistry, absorption and metabolism, mechanisms of action and toxicology as

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Current Aspects of Flavonoids: Their Role in Cancer Treatment

Current Aspects of Flavonoids: Their Role in Cancer Treatment

Hardeep Singh Tuli Editor

Current Aspects of Flavonoids: Their Role in Cancer Treatment

Editor Hardeep Singh Tuli Department of Biotechnology Maharishi Markandeshwar (Deemed to be University) Mullana-Ambala, Haryana, India

ISBN 978-981-13-5873-9    ISBN 978-981-13-5874-6 (eBook) https://doi.org/10.1007/978-981-13-5874-6 © Springer Nature Singapore Pte Ltd. 2019 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Singapore Pte Ltd. The registered company address is: 152 Beach Road, #21-01/04 Gateway East, Singapore 189721, Singapore

“This Book is Dedicated to Beloved Parents”

Preface

Cancer is a major cause of death worldwide and becomes the biggest killer in the twenty-first century. It has been ranked second in mortality rate following cardiovascular diseases in most of the countries. Every year, the number of people being diagnosed with cancer is increasing very fast. Due to the lack of significant improvement in diagnosis, treatment, and prevention, cancer has or will soon become the number one killer in most parts of the world. Induced side effects and acquired resistance against anticancer drugs create the hassle for the treatment of cancer and enthusiasm for the development of new approaches. Epidemiological studies show a cancer-protective effect of diets rich in fruits and vegetables and develop a possibility of curing cancer with biologically active plant secondary metabolites. There are huge groups of such compounds, collectively called “phytochemicals,” which provide flavour and colour to edible plants. Flavonoids are one among such kind of compounds that exert anticarcinogenic effects in various animal models of cancer. A great progress has al