Discriminant Validity

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Glossary

reason for incorporating a discount rate into the calculations of years of life lost is to offset the use of funds for prevention and treatment in current populations and the redistribution of funds to future eradication programs.

Discounting Definition A method to account for the assumption that a current year is worth more than a future year of healthy life. Discounting is widely used in economic and financial calculations, for example to calculate constant dollars, as well and in economic evaluations of health and public health interventions, including cost-effectiveness studies.

Discriminant Validity Definition Discriminant Validity is the ability of an instrument to differentiate between patients with varying degrees of disease severity.

Discriminate Synonyms Differentiate; Classify Definition The ability to distinguish between conditions e.g. treatments, or other factors of interest.

Disease Activity Definition A measure of how severe a disease is in a patient. It is based upon several factors such as number of abnormal incidences, the need to take medication, blood count and other manifestations. It is commonly used to determine effectiveness of medications.

Disease Activity Score Definition DAS is a measure of disease activity. For example, with respect to rheumatoid arthritis, it is a formula incorporating clinical variables (number of tender and swollen joints, patient assessment of disease activity) and laboratory variable (erythrocyte sedimentation rate or C-reactive protein level). The DAS is mainly used for assessing treatment response in clinical trials but is increasingly used in clinical practice as a guide to treatment decisions.

Disease Burden Definition The quantity and impact of a disease on a group of people, often over a specified period of time.

Disease Incidence – Prevalence –Mortality Models Definition Mathematical models in which standard ratios are derived and applied to situations in which data is scarce for incidence (number of new cases within a population), prevalence (total number of cases within a population), and mortality (number of condition-related deaths within a population).

Disease Modifying Antirheumatic Drugs Definition DMARDs are a group of chemical agents that reduces the inflammation and retards joint destruction and disability caused by RA. These agents are the main treatment of RA but 2–3 months are required to achieve maximum effect.