Dynamics of Immune Activation in Viral Diseases
This book discusses various components of the innate and adaptive immune response in combating viral infections, presenting the recent advances in our understanding of innate immunity recognition of viruses and highlighting the important role of inflammat
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amics of Immune Activation in Viral Diseases
Dynamics of Immune Activation in Viral Diseases
Pallaval Veera Bramhachari Editor
Dynamics of Immune Activation in Viral Diseases
Editor Pallaval Veera Bramhachari Department of Biotechnology Krishna University Machilipatnam, Andhra Pradesh, India
ISBN 978-981-15-1044-1 ISBN 978-981-15-1045-8 (eBook) https://doi.org/10.1007/978-981-15-1045-8 © Springer Nature Singapore Pte Ltd. 2020 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Singapore Pte Ltd. The registered company address is: 152 Beach Road, #21-01/04 Gateway East, Singapore 189721, Singapore
Preface
Viral infectious diseases signify an essential portion of global public health concern with millions of deaths annually. Viruses produce disease directly by killing the host cells they infect or by liberating toxins that can cause tissue damage and functional derangements in neighboring or distant cells and tissues. In the field of viral immunology, the researchers continue to make noteworthy and exhilarating contributions to our understanding of the fundamental biology of the immune system. Yet the practical translational applications of this fascinating and enthralling area of science are little disappointing with regard to the recurrent viral outbreaks. The development of an infectious disease in an individual involves complex interactions between the virus and the host. These interactions are a dynamic interplay of host mechanisms aimed at eliminating infections and viral strategies designed to permit survival in the face of beneficial activation of innate and adaptive immune responses. Different types of infectious viral agents stimulate distinct types of immune responses and have evolved unique mechanisms for evading immunity. Noteworthy, in many instances, virus-ind
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