Editorial commentary on the Indian Journal of Gastroenterology May-June 2020
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EDITORIAL
Editorial commentary on the Indian Journal of Gastroenterology May-June 2020 Jimmy K Limdi 1,2
# Indian Society of Gastroenterology 2020
“Learn from yesterday, live for today and hope for tomorrow. And never stop questioning.” -Albert Einstein The emergence of the Severe Acute Respiratory Syndrome Corona Virus-2 (SARS-COV 2) from Wuhan, China in December 2019 and the resulting Corona Virus Disease (COVID-19) has gripped the world in a global pandemic from its unprecedented spread, changing our perceptions and paradigms around disease and the world, as we have known it. As of 11 July 2020, there have been 12,322,395 confirmed cases of COVID-19, including 556,335 deaths, reported to WHO [1] with 22,123 deaths in India [2]. Even as the world remains under the influence of this cataclysmic crisis, the medical and scientific communities have continued to work tirelessly and collaboratively to find answers for this hitherto unknown disease. Although a predominantly respiratory disease with multi-systemic ramifications, gastrointestinal (GI) symptoms such as diarrhea, vomiting, abdominal pain and hepatic abnormalities have been reported in up to 20% of patients with COVID-19, including those with minimal symptoms [3, 4]. The potential for SARS-COV2 to affect the GI tract and implications to patients with underlying GI and liver disease are of particular relevance to gastroenterologists. With this in mind, this issue focusses on COVID-19 with a series of research articles and clinical reviews on COVID-19 and GI disease, constituting essential and timely reading for the practising gastroenterologist. We hope you find these useful. And we wish you and your patients well…
* Jimmy K Limdi [email protected] 1
Inflammatory Bowel Diseases, Division of Gastroenterology, The Pennine Acute Hospitals NHS Trust, Manchester M8 5RB, UK
2
Manchester Academic Health Sciences, University of Manchester, Manchester M8 5RB, UK
Voluntary perioperative colorectal cancer registry from Kerala – an initial overview Colorectal cancer (CRC) ranks among the six most common malignancies in India; yet, outcomes data outside of selected centers are lacking [5]. Krishnan and colleagues report the first outcomes data from 1018 CRC cases from 15/25 participating centers of the Association of Surgical Gastroenterologists of Kerala CRC registry between 2016 and 2018 [6]. The majority of CRC cases were rectal (39.88%) and rectosigmoid (20.33%), with minimally invasive surgery (MIS) performed in 73% cases and 56.74% of colonic malignancies. MIS was associated with reduced length of hospital-stay compared to the open approach (10.46 ± 5.08 vs. 12.26 ± 6.03 days; p=0.001and 10.29 ± 4.58 vs. 12.46 ± 6.014 days; p=89 demonstrated an increased risk of F4 fibrosis. No differences were noted in NLR values for both groups. Further studies in well-characterized cohorts incorporating liver biopsy are now needed to validate these findings.
Decreasing major surgical rates for Crohn's disease in an emerging economy over two decades but is it due to bio
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