Esophageal Cancer Diagnosis and Treatment
This book provides comprehensive and practical guidance for the management of esophageal cancer. It presents a detailed review of the pathophysiology, clinical staging, treatment, and outcomes of patients with esophageal cancer. Chapters cover t
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Esophageal Cancer
Francisco Schlottmann Daniela Molena • Marco G. Patti Editors
Esophageal Cancer Diagnosis and Treatment
Editors Francisco Schlottmann Hospital Alemán of Buenos Aires University of Buenos Aires Buenos Aires Argentina
Daniela Molena Memorial Sloan Kettering Cancer Center New York, NY USA
Marco G. Patti University of North Carolina at Chapel Hill Chapel Hill, NC USA
ISBN 978-3-319-91829-7 ISBN 978-3-319-91830-3 (eBook) https://doi.org/10.1007/978-3-319-91830-3 Library of Congress Control Number: 2018951923 © Springer International Publishing AG, part of Springer Nature 2018 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by Springer Nature, under the registered company Springer International Publishing AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
To our mothers, with gratitude for their unconditional support of our quest for a better education Maria Cristina Pozzi Luigina Bondesan Ada Travali Patti
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Preface
Esophageal cancer is the eighth most common cancer worldwide, with an estimated 456,000 new cases and 400,000 deaths in 2012. About 87% of all esophageal cancers globally are squamous cell carcinomas, with the highest incidence rates in populations within South-Eastern and Central Asia, Eastern Africa, and South America. Only 11% of all esophageal cancers are esophageal adenocarcinomas, with an elevated burden seen in Northern and Western Europe, Oceania, and Northern America. Over the past 40 years, however, the incidence of esophageal adenocarcinoma has increased more than sixfold in Western countries. This increased incidence has been mostly attributed to the rising prevalence of obesity and gastroesophageal reflux disease. This evidence- and experience-based book represents the collaboration of leading centers in the world in the treatment of
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