Evaluation of emulsified silicone oil with spectral domain-optical coherence tomography and fluorescein angiography

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ORIGINAL PAPER

Evaluation of emulsified silicone oil with spectral domainoptical coherence tomography and fluorescein angiography Zafer Cebeci . Muhammed Talha Sadik . Mehmet Bedii Ogurel . Emre Altinkurt . Nur Kir

Received: 16 March 2020 / Accepted: 2 May 2020 Ó Springer Nature B.V. 2020

Abstract Background To report emulsified particles and related complications after removal of silicone oil (SO) by spectral domain-optical coherence tomography (SD-OCT) and fluorescein angiography (FA). Methods A prospective, single-center investigation was performed using SD-OCT, FA and flare cell photometry measurements to evaluate in a cohort of eyes with emulsified silicone particles after removal of long-term SO tamponade. Results Nineteen eyes of the 19 patients with emulsified silicone particles detected in ophthalmoscopic exam were included in the study: 13 (68%) were male, and 6 (31.6%) were female, and their mean Z. Cebeci (&)  M. T. Sadik  M. B. Ogurel  E. Altinkurt  N. Kir Ophthalmology Department, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey e-mail: [email protected] M. T. Sadik e-mail: [email protected] M. B. Ogurel e-mail: [email protected] E. Altinkurt e-mail: [email protected] N. Kir e-mail: [email protected] Z. Cebeci I.U. Istanbul Tip Fakultesi Go¨z Hastalikları AD Capa, Fatih, Istanbul, Turkey

age was 52.75 ± 16.06 years. Preoperative diagnoses were rhegmatogenous retinal detachment in all eyes. The mean duration of the silicone oil’s presence in the eye was found as 12.63 ± 4.87 (7–26) months. SDOCT examination postoperatively showed small, round and hyper-reflective structures compatible with emulsified silicone particles on preretinal surface in 7 (36.8%) eyes, intraretinally in 6 (31.6%) eyes and in the vitreous in 12 (63%) eyes. FA imaging demonstrated pearl-like hyper-fluorescence at early and late phases on the large blood vessels in 9 (47.4%) eyes. Late phase hyper-fluorescence due to leakage on the macula was observed in 17 (89.5%) eyes. Diffuse peripheral leakage and hyper-fluorescence was detected in 11 (57.9%) eyes. Flare levels were higher in eyes with emulsified SO compared to unaffected fellow eyes (p \ 0.05). Conclusions Emulsified silicone particles that remain in the eye may lead to retinal complications and inflammation in addition to their known complications such as keratopathy and glaucoma. The particles that lead to inflammation and presence of inflammation may be examined by imaging methods such as SD-OCT and FA. Removing the SO before emulsification would be suitable for avoiding such complications. Keywords Optical coherence tomography  Fluorescein angiography  Flare  Silicone  Emulsification

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Int Ophthalmol

Background Silicone oil (SO) is an intraocular tamponade that has been used in vitreoretinal surgery for the treatment of complex retinal pathologies for years [1]. However, it is known that SO which is used as a tamponade may lead to various side effects in the short or long pe