Gastric glomus tumor: A case report
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WORLD JOURNAL OF SURGICAL ONCOLOGY
CASE REPORT
Open Access
Gastric glomus tumor: A case report Ioannis Vassiliou1*, Aliki Tympa2, Theodosios Theodosopoulos1, Nikolaos Dafnios1, Georgios Fragulidis1, Andreas Koureas3, Evi Kairi4
Abstract Gastric glomus tumors are rare mesenchymal tumors of the gastrointestinal tract. We describe a 72-year-old patient who presented with episodes of melena and was subsequently investigated for a tumor of the antrum of the stomach. Surgical resection revealed a 2 × 2 × 1.7 cm well circumscribed submucosal tumor, extending into the muscularis propria. The histopathologic examination of the specimen demonstrated a glomus tumor of the stomach. We discuss the preoperative investigation, the diagnostic problems and the surgical treatment of the patient with this rare submucosal lesion. Background Glomus tumors are benign neoplasms of well-differentiated mesenchymal cells. Glomus tumors of the stomach are rare lesions, arising in the intramuscular layer. They typically present as a solitary submucosal nodule in the region of the antrum and pylorus. Preoperative diagnosis of gastric glomus tumors is difficult and requires a multi-faculty medical approach. We present a rare case of a glomus tumor of the stomach along with the investigative procedures and the surgical treatment. Case Presentation Two months ago, a 72-year-old woman presented to her primary care physician with an episode of melena that was suggestive of hemorrhage of the upper gastrointestinal tract. Upon presentation the patient was hemodynamically stable with normal laboratory tests and no evidence of active bleeding in the last 48 hours. Hospitalization was not required and the evaluation was completed in the outpatient department. The patient was subjected to further investigation. Upper gastrointestinal endoscopy revealed mild, diffuse oesophagitis and a small sliding hiatal hernia. At the antrum of the stomach, a 5 cm, well circumscribed submucosal mass with normal overlying mucosa was observed (Figure 1). Multiple regular biopsies were taken and some histological features of leiomyoma were identified. An endoscopic ultrasound confirmed the submucosal lesion which originated from the muscularis * Correspondence: [email protected] 1 Second Department of Surgery, Athens Medical School, Aretaieion Hospital, 76 Vassilisis Sofias Avenue, 11528, Athens, Greece
propria, measured 1.9 × 2.4 cm and was extending in the second, third and fourth layer of the stomach. The patient was subsequently referred for surgical consultation. Physical examination revealed a 72-yearold female who was awake and alert, appeared healthy and looked younger than her stated age. Her abdomen was soft, non-distended, without palpable masses. The stool was negative for occult blood. The hemoglobin level was 13.1 g/dL with normal biochemical profile. Tumor markers were within reference ranges. Abdominal radiography showed normal amount and distribution of gas within the bowel. An abdominal computer tomography scan demonstrated a 3 cm localized, prepylo
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