Genome Mapping and Genomics in Human and Non-Human Primates

This book provides an introduction to the latest gene mapping techniques and their applications in biomedical research and evolutionary biology. It especially highlights the advances made in large-scale genomic sequencing. Results of studies that illustra

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apping and Genomics in Human and NonHuman Primates

Genome Mapping and Genomics in Animals Volume 5

Series editor Chittaranjan Kole, Mohanpur, India

For further volumes: http://www.springer.com/series/7518

Ravindranath Duggirala Laura Almasy Sarah Williams-Blangero Solomon F.D. Paul Chittaranjan Kole •



Editors

Genome Mapping and Genomics in Human and Non-Human Primates

123

Editors Ravindranath Duggirala South Texas Diabetes and Obesity Institute University of Texas Health Science Center at San Antonio Edinburg, TX USA Laura Almasy South Texas Diabetes and Obesity Institute University of Texas Health Science Center at San Antonio San Antonio, TX USA

Solomon F.D. Paul Faculty of Biomedical Sciences, Technology and Research Sri Ramachandra University Chennai India Chittaranjan Kole Bidhan Chandra Krishi Viswavidyalaya Mohanpur, West Bengal India

Sarah Williams-Blangero South Texas Diabetes and Obesity Institute Brownsville, TX USA

Genome Mapping and Genomics in Animals ISBN 978-3-662-46305-5 ISBN 978-3-662-46306-2 DOI 10.1007/978-3-662-46306-2

(eBook)

Library of Congress Control Number: 2015932067 Springer Heidelberg New York Dordrecht London © Springer-Verlag Berlin Heidelberg 2015 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper Springer-Verlag GmbH Berlin Heidelberg is part of Springer Science+Business Media (www.springer.com)

Preface

In recent years, there has been phenomenal progress in the understanding of the genetic architecture of normal and disease-related complex phenotypes. The progress has been fueled by an explosion of research activities related to the Human Genome Project and subsequent sequencing projects, and the nonhuman primate comprehensive sequencing projects. Advances in molecular genetics, statistical genetics, medical genetics, and bioinformatics have accompanied this progress. Tracing its roots back to the laws of inheritance established by Mendel, which continue to be the basic tenets underlying modern gene