Headache in a group of SARS-COVID-19 patients: an observational prospectical study
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Headache in a group of SARS-COVID-19 patients: an observational prospectical study Alfonso Coppola 1,2,3 & Maria Clara Tonini 4 & Elena Baratelli & Caterina Barillà & Roberto Bassani & Elda Fabiola Gonano & Franco Grassi & Ilaria Guidi & Federica Lucchelli & Davide Mantica & Marco Mattioli & Gabriella Perri & Maria Grazia Riggio & Marco Ronzoni & Marco Tiriticco & Alessandra Vanotti & Garbagnate Covid Group
# Fondazione Società Italiana di Neurologia 2020
Despite the recent outbreak of SARS-COVID-19 is mainly characterized by respiratory symptoms, neurological involvement has been reported in several cases, in which extended review, Ling Mao and colleagues [1] have described different neurological symptoms, with an involvement of the central nervous system (CNS), the peripheral nervous system (PNS), and the skeletal muscular injury. Headache is present in 13% of these patients, but the authors do not specify its characteristics and its relationship with the clinical features of COVID-19 [2, 3]. In this study, we report the findings of a small group of patients that have been hospitalized in order to better characterize the specific type of their cephalic pain. We have evaluated 73 patients in total (mean age 69.75), 52 of whom were males (mean age: 70.55) and 21 were females (mean age: 67.66). The patients have been treated with oxygen at different flow depending on their clinical state, drugs as antibiotics when necessary, antimalarial drug (hydroxychloroquine) and steroids when needed, but most importantly they have been asked multiple questions in order to better characterize their type of headache (we left out all the patients that were unable to provide reliable answers). No one has been evaluated with CT scan, but all patients had a normal neurological
* Alfonso Coppola [email protected]; [email protected] 1
Department of Neurology, G. Salvini Hospital, Garbagnate Milanese, Italy
2
Headache Center, G. Salvini Hospital, Garbagnate Milanese, Italy
3
Department of Neurology and Headache Center, G. Salvini Hospital, Viale E. Forlanini 95, 20024 Garbagnate Milanese, Italy
4
Service of Neurology and Headache Center, S. Carlo Clinic, Paderno Dugnano, Italy
examination: they did not have any clinical sign of impairment of the CNS/PNS or any other neurological symptom. In the male group, 49 subjects did not complain about having headache (67.1%), while 3 patients reported headache during hospitalization (5.7%): 2 men suffered from tension type headache (TTH) only during hospitalization, whereas 1 patient complained about migraine without aura (MO) both during hospitalization and at home. In the female group, 5 patients had pain during hospitalization (23.8 %): MO was present in 2 of them (9.5%), whereas TTH was reported by the other 3 (14.28%). Among these 5 women, 3 complained about pain also at home (1 MO/1 TTH/ 1 with MO and TTH). Seven women out of 21 complained about pain at home: 5 referred pain with TTH characteristics (one of them suffered from both type of pain MO and
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