Health-related quality of life in children and adolescents undergoing intraoperative device closure of isolated perimemb
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(2019) 14:218
RESEARCH ARTICLE
Open Access
Health-related quality of life in children and adolescents undergoing intraoperative device closure of isolated perimembranous ventricular septal defects in southeastern China Jiang-Shan Huang1,2†, Shu-Ting Huang1,2†, Kai-Peng Sun1,2, Zhi-Nuan Hong1,2, Liang-Wan Chen1, Yur-Ren Kuo3 and Qiang Chen1*
Abstract Objectives: To investigate the health-related quality of life (HRQOL) in children and adolescents who underwent intraoperative device closure of perimembranous ventricular septal defects (pmVSDs). Methods: From October 2017 to January 2018, a total of 126 children and adolescents with isolated pmVSDs who underwent intraoperative device closure were enrolled in this study. We used the Pediatric Quality of Life Inventory Measurement Models 4.0 generic core scales to measure HRQOL 24 h before the operation and three months and one year after surgery. Results: A total of 126 patients were successfully occluded. No severe complications occurred during the operative time, and 1 case of Mobitz type I atrioventricular block (AVB) and 1 case of complete cAVB occurred during the postoperative period. Compared with the data before the operation, the total score and five domain scores, including physical, psychosocial, emotional, social and psychological functioning, were significantly higher at three months after the operation. In addition, the total score, physical functioning score, and the psychosocial functioning score at the 1-year follow-up were even higher than those at 3 months after the operation. Conclusions: The present study suggests that intraoperative device closure of pmVSD could improve health-related quality of life in children/adolescents and that the improvement may progress as the time after the operation increases. Further studies should concentrate on comparisons with other medical methods, larger samples, and longer follow-up periods. Keywords: Health-related quality of life, Children, Adolescents, Ventricular septal defect, Intraoperative device closure
* Correspondence: [email protected] † Jiang-Shan Huang and Shu-Ting Huang are contributed equally to this study and share first authorship 1 Department of Cardiovascular Surgery, Union Hospital, Fujian Medical University, Fuzhou 350001, People’s Republic of China Full list of author information is available at the end of the article © The Author(s). 2019 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
Huang et al. Journal of Cardiothoracic Surgery
(2019) 14:218
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