Health-related quality of life measured using EQ-5D in patients with lymphomas
- PDF / 443,231 Bytes
- 12 Pages / 595.276 x 790.866 pts Page_size
- 84 Downloads / 163 Views
ORIGINAL ARTICLE
Health-related quality of life measured using EQ-5D in patients with lymphomas Richard Huan Xu 1 & Eliza Lai-yi Wong 1 & Jun Jin 2 & Huiqiang Huang 3 & Dong Dong 1 Received: 25 May 2020 / Accepted: 10 September 2020 # Springer-Verlag GmbH Germany, part of Springer Nature 2020
Abstract Purpose This study aimed to estimate the health preference–based index scores of the population of patients with lymphoma using the EQ-5D in China. Methods A cross-sectional online survey was conducted to examine the health and well-being of patients with lymphoma in China. Their health-related quality of life (HRQoL; using the EQ-5D), demographic and socioeconomic characteristics, and health conditions were assessed. The data were analyzed using Pearson’s χ2 test, analysis of variance, and binary logistic and Tobit regression models. Results A total of 3261 patients (sex: men = 58.5%, age: < 30 years = 9.5% and > 60 years = 24.6%) participated in the study. The mean EQ-5D-5L index and EQ-VAS scores were 0.83 and 68.8, respectively. Binary logistic regression analysis revealed that women reported more pain-related problems than men did. Unemployed participants were substantially more likely to report health problems on all the five dimensions of the EQ-5D than their employed counterparts. The Tobit regression model revealed that respondents who were older, unemployed, with low income, received chemotherapy, and with short durations reported a low index score. Conclusion Using the EQ-5D, the preference-based scores of different subpopulations of patients with lymphoma may support economic evaluation by promoting the simultaneous consideration of both the reasonable use of resources and satisfactory achievement of health outcomes. Keywords Health-related quality of life . Lymphoma . EQ-5D . China
Introduction Lymphoma is a cancer that originates in the lymphatic system. It develops in lymphocytes and can quickly spread to different Electronic supplementary material The online version of this article (https://doi.org/10.1007/s00520-020-05774-6 ) contains supplementary material, which is available to authorized users. * Dong Dong [email protected] 1
The Jockey Club School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong SAR, China
2
Department of Sociology, School of Social Sciences, Tsinghua University, Beijing, China
3
Department of Medical Oncology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China
organs [1]. There are two main types of lymphoma: Hodgkin (HL) and non-Hodgkin (NHL) lymphoma. HL is curable and usually has a good prognosis. In contrast, NHL has several subtypes and is more lethal [1]. Lymphoma is one of the most common hematologic malignancies worldwide and has been listed as the fifth, sixth, and eighth (NHL) most common types of cancer in the United Kingdom (UK) [2], Australia [3], and the USA [4], respectively. In China, lymphoma is the eleventh most c
Data Loading...
