Hepatology and Transplant Hepatology A Case Based Approach

Hepatology and Transplant Hepatology: A Case Based Approach presents a collection of interesting cases in liver disease seen at a very busy and large liver transplant center in the United States. These cases cover the full range of pathology that an inter

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Jawad Ahmad, MD, FRCP

Hepatology and Transplant Hepatology A Case Based Approach

With Contributions by Shahid M. Malik MD, Assistant Professor of Medicine, Division of Gastroenterology, Hepatology & Nutrition, University of Pittsburgh School of Medicine, Pittsburgh, PA James S. Park, MD, CNSC, Assistant Professor of Medicine, Division of Liver Diseases, Mount Sinai Liver Cancer Program, Recanati-Miller Transplantation Institute, Mount Sinai School of Medicine, New York, NY David A. Sass, MD, Associate Professor of Medicine and Surgery, Associate Chief, Division of Gastroenterology and Hepatology, Drexel University College of Medicine, Philadelphia, PA

Jawad Ahmad, MD, FRCP Associate Professor of Medicine Division of Liver Diseases Recanati-Miller Transplantation Institute Mount Sinai School of Medicine NewYork, NY USA [email protected]

ISBN 978-1-4419-7084-8 e-ISBN 978-1-4419-7085-5 DOI 10.1007/978-1-4419-7085-5 Springer New York Dordrecht Heidelberg London Library of Congress Control Number: 2010937227 © Springer Science+Business Media, LLC 2011 All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Springer Science+Business Media, LLC, 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer soft-ware, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)

Preface

Over the last few decades, hepatology and transplant hepatology have emerged as individual disciplines, separate from gastroenterology, and this has been recognized by the American Board of Internal Medicine who have offered a transplant hepatology board examination since 2006. In the USA and Europe, there are increasing numbers of specialists who consider themselves exclusively as hepatologists, and even among this group there is differentiation into nontransplant and transplant hepatology. Many textbooks of medicine are an excellent reference source but are difficult to read. For students and trainees, a basic understanding of epidemiology and pathogenesis of disease entities are important but management of a specific clinical condition mirrors the real world (and many examination situations). A patient rarely presents with acute hepatitis B or with primary sclerosing cholangitis but is much more likely to present with an acute hepatitis or abnormal liver enzymes. Similarly, patients after liver transplantation present with symptoms or abnormal blood tests or imaging rather than a specific diagnosis. The way to approach su