Immunity to Blood Parasites of Animals and Man

Since the turn of the century, certain parasitic diseases of livestock have frus­ trated efforts to bring them under control by vaccination techniques; East Coast fever and trypanosomiasis are two such diseases. East Coast fever (ECF) kills a half million

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ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY Editorial Board: Nathan Back

State University of New York at Buffalo

N. R. Di Luzio

Tulane University School of Medicine

Bernard Halpern

College de France and Institute of Immuno·Biology

Ephraim Katchalski

The Weizmann Institute of Science

David Kritchevsky

Wistar Institute

Abel Lajtha

New York State Research Institute for Neurochemistry and Drug Addici

Rodolfo Paoletti

University of Milan

Recent Volumes in this Series Volume 86A PROTEIN CROSSLINKING: Biochemical and Molecular Aspects Edited by Mendel Friedman. 1977 Volume 86B PROTEIN CROSSLINKING: Nutritional and Medical Consequences Edited by Mendel Friedman. 1977 Volume 87 HYPOTHALAMIC PEPTIDE HORMONES AND PITUITARY REGULATION Edited by John C. Porter. 1977 Volume 88 AVIAN IMMUNOLOGY Edited by Albert A. Benedict. 1977 Volume 89 MUCUS IN HEALTH AND DISEASE Edited by Max Elstein and Dennis V. Parke. 1977 Volume 90 PARKINSON'S DISEASE: Neurophysiological, Clinical, and Related Aspects Edited by Fathy S. Messiha and Alexander D. Kenny. 1977 Volume 91 INORGANIC AND NUTRITIONAL ASPECTS OF CANCER Edited by G. N. Schrauzer. 1977 Volume 92 MORRIS HEP ATOMAS: Mechanisms of RegUIation Edited by Harold P. Morris and Wayne E. Criss .1977 Volume 93 IMMUNITY TO BLOOD PARASITES OF ANIMALS AND MAN Edited by Louis H. Miller, John A. Pino, and John J. McKelvey, Jr.• 1977 Volume 94 OXYGEN TRANSPORT TO TISSUE-III Edited by I. A. Silver, M. Erecinska, and H. I. Bicher .1977 Volume 95 ACID PROTEASES: Structure, Function, and Biology Edited by Jordan Tang. 1977

IMMUNITY TO BLOOD PARASITES OF ANIMALS AND MAN Edited by

Louis H. Miller National Institute of Allergy and Infectious Diseases Bethesda, Maryland

and

John A. Pino and John J. McKelvey, Jr. The Rockefeller Foundation New York, New York

PLENUM PRESS • NEW YORK AND LONDON

Library of Congress Cataloging in Publication Data Main entry under title: Immunity to blood parasites of animals and man. (Advances in experimental medicine and biology; v. 93) "Based on papers presented at the Rockefeller Foundation Study and Conference Center at Bellagio, Italy, September, 1975." Includes indexes. 1. Medical parasitology-Immunological aspects-Congresses. 2. Veterinary parasitology-Immunological aspects-Congresses. 3. Vaccination-Congresses. 4. Vaccination of animals-Congresses. I. Miller, Louis H. II. Pino, John A. III. McKelvey, John J. IV. Series. [DNLM: 1. Antigens-Congresses. 2. Immunization-Congresses. 3. Parasitic diseases-Congresses. 4. Parasitic diseases- Veterinary-Congresses. WIAD559 v. 93/WC695 1311975] RC157.I45 616.9'6 77-16094

ISBN-13: 978-1-4615-8857-3 DOl: 10.1007/978-1-4615-8855-9

e-ISBN-13: 978-1-4615-8855-9

Based on papers presented at the Rockefeller Foundation Study and Conference Center at Bellagio, Italy, September, 1975

© 1977 Plenum Press, New York Softcover reprint of the hardcover 1st edition 1977

A Division of Plenum Publishing Corporation 227 West 17th Street, New York, N.Y. 10011 All rights reserved No part of this book may be reproduced, sto