Impact of pandemic COVID-19 outbreak on oral mucositis preventive and treatment protocols: new perspectives for extraora
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COMMENTARY
Impact of pandemic COVID-19 outbreak on oral mucositis preventive and treatment protocols: new perspectives for extraoral photobiomodulation therapy Karina Morais Faria 1 & Wagner Gomes-Silva 1,2 & Elisa Kauark-Fontes 3 & Carolina Guimarães Bonfim-Alves 1,3 & Luiz Paulo Kowalski 4 & Ana Carolina Prado-Ribeiro 1,3 & Aljomar José Vechiato-Filho 1 & Marcio Ajudarte Lopes 3 & Gustavo Nader Marta 5,6 & Gilberto de Castro Jr 7 & Adriana Franco Paes Leme 8 & Cesar Augusto Migliorati 9 & Alan Roger Santos-Silva 3 & Thaís Bianca Brandão 1 Received: 28 April 2020 / Accepted: 15 July 2020 # Springer-Verlag GmbH Germany, part of Springer Nature 2020
Abstract This communication discusses the current challenges of oral mucositis (OM) management during the pandemic COVID-19 outbreak and reflects about an extraoral photobiomodulation protocol as an optimal alternative for preventing and treating OM in advanced cancer patients while minimizing the risk of infection by avoiding intraoral manipulation. Keywords COVID-19 . Oral mucositis . Cancer . Photobiomodulation therapy . Laser therapy
Introduction The recent 2019 novel coronavirus disease (COVID-19) pandemic has dramatically changed several aspects of worldwide communities, evoking many changes in the routine activities of populations as well as impacting economic burden and functioning capacity of the healthcare system [1]. Since December 2019, when the first cases emerged in Wuhan (Hubei Province of China) [2, 3], an exponential number of infected patients with the SARS coronavirus 2 (SARS-CoV2), the known etiologic agent of the COVID-19, has spread across multiple countries with rapid community dissipation of the virus [4, 5]. Acute inflammatory distress syndrome is one
* Alan Roger Santos-Silva [email protected] 1
Dental Oncology Service, Instituto do Câncer do Estado de São Paulo (ICESP), São Paulo, Brazil
2
Medical School, Nove de Julho University, UNINOVE, São Paulo, Brazil
3
Oral Diagnosis Department, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, Brazil
4
Head and Neck Surgery Department, University of Sao Paulo Medical School and Department of Head and Neck Surgery and Otorhinolaryngology A C Camargo Cancer Center, São Paulo, Brazil
of the most life-threatening complications of COVID-19 and usually requires intensive care and mechanical ventilation [1], most frequently in more vulnerable patients, which include patients undergoing anticancer treatment or diagnosed with malignancies associated with an immunosuppressive state. Cumulative evidence suggests that cancer patients are at increased risk of COVID-19 infection [6], and early published reports estimated a significant higher risk of mortality over 3.5 times on cancer patients [7]. The person-to-person spread of COVID-19 disease seems to be rapid and may quickly overwhelm the care settings from primary to tertiary levels. In this scenario, oncologic care facilities have faced the dilemma of how to maintain cancer
5
Division of Radiation Oncology, Instituto do
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