Impact of sub-foveal choroidal thickness on clinical features and long-term clinical outcomes in polypoidal choroidal va
- PDF / 816,902 Bytes
- 11 Pages / 547.087 x 737.008 pts Page_size
- 20 Downloads / 161 Views
(0123456789().,-volV) ( 01234567 89().,-volV)
ORIGINAL PAPER
Impact of sub-foveal choroidal thickness on clinical features and long-term clinical outcomes in polypoidal choroidal vasculopathy Ramesh Venkatesh . Santosh Gopi Krishna Gadde . Arpitha Pereira . Vivek Singh . Sajjan Sangai . Akhila Sridharan . Bharathi Bavaharan . Nimesh Jain . Naresh Kumar Yadav
Received: 17 May 2020 / Accepted: 16 August 2020 Ó Springer Nature B.V. 2020
Abstract Purpose To study the clinical features and long-term clinical outcomes in polypoidal choroidal vasculopathy (PCV) in eyes with different sub-foveal choroidal thickness (SFCT). Methods In this retrospective, observational comparative study, treatment-naı¨ve eyes diagnosed with PCV using the ‘EVEREST-2’ study criteria were included. The eyes were divided into three groups of thin, medium and thick choroids, based on the SFCT data of total study eyes. Demographic, clinical, imaging features and treatment outcomes between the 3 groups were compared. Results Sixty-three eyes in 63 patients were included. Right eye was involved in 39 (61%) cases and left eye in 24 (39%) cases. Mean age was 68.3 ± 6.82 years (range 54–85 years). Mean SFCT was 274 lm (median = 269 lm), and one standard deviation was 79.2 lm. Totally, 11, 43 and 9 eyes were included in the thin, medium and thick choroid groups, respectively. The mean SFCT was 161 ± 24.1 lm, 275 ± 39.6 lm and 412 ± 26.2 lm in the thin, medium and thick choroid
R. Venkatesh (&) S. G. K. Gadde A. Pereira V. Singh S. Sangai A. Sridharan B. Bavaharan N. Jain N. K. Yadav Department of Retina-Vitreous, Narayana Nethralaya, 121/C, Chord Road, 1st ‘R’ Block, Rajaji Nagar, Benguluru 560010, India e-mail: [email protected]
groups, respectively. There was no statistically significant difference in the clinical and imaging features and treatment outcomes between eyes with thin, medium and thick SFCT. Conclusion Eyes with PCV can have a choroid of varying thicknesses. Clinical, imaging and treatment responses were similar between the three sub-foveal choroidal thickness groups in this study. In future, more studies are required to evaluate the role of the choroidal thickness and its relationship to treatment in PCV. Keywords Polypoidal choroidal vasculopathy Choroidal thickness Optical coherence tomography Outcome
Background Polypoidal choroidal vasculopathy (PCV) has been classified as one of the disease entities that fall under the pachychoroid spectrum, as described by Cheung et al. and Lee et al. [1, 2]. PCV is an exudative retinal disease commonly seen in Asians and is typically characterized by a thickened sub-foveal choroid, dilated choroidal vessels, a double-layer sign at the level of the retinal pigment epithelium–Bruch’s membrane–choriocapillaris complex, and hyperreflectivity between the retinal pigment epithelium and Bruch’s membrane [3–5].
123
Int Ophthalmol
Several studies have classified PCV based on its angiographic features on fluorescein angiography and indocyanine green angiography and have also
Data Loading...
