Irreversible Electroporation
This is an brief introduction to the emerging field of irreversible electroporation in medicine. Certain electrical fields when applied across a cell can have as a sole effect the permeabilization of the cell membrane, presumable through the formation of
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Series in Biomedical Engineering Editor-in-Chief Prof. Dr. Joachim H. Nagel Institute of Biomedical Engineering University of Stuttgart Seidenstrasse 36 70174 Stuttgart Germany E-mail: [email protected] The International Federation for Medical and Biological Engineering, IFMBE, is a federation of national and transnational organizations representing internationally the interests of medical and biological engineering and sciences. The IFMBE is a non-profit organization fostering the creation, dissemination and application of medical and biological engineering knowledge and the management of technology for improved health and quality of life. Its activities include participation in the formulation of public policy and the dissemination of information through publications and forums. Within the field of medical, clinical, and biological engineering, IFMBE’s aims are to encourage research and the application of knowledge, and to disseminate information and promote collaboration. The objectives of the IFMBE are scientific, technological, literary, and educational. The IFMBE is a WHO accredited NGO covering the full range of biomedical and clinical engineering, healthcare, healthcare technology and management. It is representing through its 58 member societies some 120.000 professionals involved in the various issues of improved health and healthcare delivery. IFMBE Officers President: Makoto Kikuchi, Vice-President: Herbert Voigt, Past-President: Joachim H. Nagel, Treasurer: Shankar M. Krishnan, Secretary-General: Ratko Magjarevic http://www.ifmbe.org
Previous Editions: Spaan, J. et al: BIOMED, Biopacemaking, 2007, ISBN 978-3-540-72109-3 Sekihara, K., Nagarajan, S.: BIOMED, Adaptive Spatial Filters for Electromagnetic Brain Imaging, 2008, ISBN 978-3-540-79369-4 Madhavan, G., Oakley, B.; Kun, L.(Eds.): BIOMED, Career Development in Bioengineering and Biotechnology, 2009, ISBN 978-0-387-76494-8
Boris Rubinsky (Ed.)
Irreversible Electroporation
ABC
Prof. Boris Rubinsky University of California, Berkeley Dept. Mechanical Engineering 6124 Etcheverry Hall Berkeley, CA 94720-1740 USA E-mail: [email protected] and Hebrew University of Jerusalem “Center for Bioengineering in the Service of Humanity and Society” Givat Ram Campus 78 Ross Bldg Jerusalem, Israel E-mail: [email protected]
ISBN 978-3-642-05419-8
e-ISBN 978-3-642-05420-4
DOI 10.1007/978-3-642-05420-4 Series in Biomedical Engineering
ISSN 1864-5763
Library of Congress Control Number: 2009938728 c 2010 Springer-Verlag Berlin Heidelberg This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilm or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright Law of September 9, 1965, in its current version, and permission for use must always be obtained from Spring
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