Malaria paediatric hospitalization between 1999 and 2008 across Kenya
- PDF / 749,405 Bytes
- 18 Pages / 610 x 792 pts Page_size
- 96 Downloads / 192 Views
BioMed Central
Open Access
Research article
Malaria paediatric hospitalization between 1999 and 2008 across Kenya Emelda A Okiro*1,2, Victor A Alegana1, Abdisalan M Noor1,2, Juliette J Mutheu1, Elizabeth Juma3 and Robert W Snow1,2 Address: 1Malaria Public Health & Epidemiology Group, Centre for Geographic Medicine Research - Coast, Kenya Medical Research Institute/ Wellcome Trust Research Programme, P.O. Box 43640, 00100 GPO, Nairobi, Kenya, 2Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, CCVTM, Oxford OX3 7LJ, UK and 3Division of Malaria Control, Ministry of Public Health and Sanitation, P.O Box 19982, 00202 KNH, Nairobi, Kenya Email: Emelda A Okiro* - [email protected]; Victor A Alegana - [email protected]; Abdisalan M Noor - [email protected]; Juliette J Mutheu - [email protected]; Elizabeth Juma - [email protected]; Robert W Snow - [email protected] * Corresponding author
Published: 9 December 2009 BMC Medicine 2009, 7:75
doi:10.1186/1741-7015-7-75
Received: 19 August 2009 Accepted: 9 December 2009
This article is available from: http://www.biomedcentral.com/1741-7015/7/75 © 2009 Okiro et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract Background: Intervention coverage and funding for the control of malaria in Africa has increased in recent years, however, there are few descriptions of changing disease burden and the few reports available are from isolated, single site observations or are of reports at country-level. Here we present a nationwide assessment of changes over 10 years in paediatric malaria hospitalization across Kenya. Methods: Paediatric admission data on malaria and non-malaria diagnoses were assembled for the period 1999 to 2008 from in-patient registers at 17 district hospitals in Kenya and represented the diverse malaria ecology of the country. These data were then analysed using autoregressive moving average time series models with malaria and all-cause admissions as the main outcomes adjusted for rainfall, changes in service use and populations-at-risk within each hospital's catchment to establish whether there has been a statistically significant decline in paediatric malaria hospitalization during the observation period. Results: Among the 17 hospital sites, adjusted paediatric malaria admissions had significantly declined at 10 hospitals over 10 years since 1999; had significantly increased at four hospitals, and remained unchanged in three hospitals. The overall estimated average reduction in malaria admission rates was 0.0063 cases per 1,000 children aged 0 to 14 years per month representing an average percentage reduction of 49% across the 10 hospitals registering a significant decline
Data Loading...
