Multiscale composite nanofiber membranes with asymmetric wetability: preparation, characterization, and applications in
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Multiscale composite nanofiber membranes with asymmetric wetability: preparation, characterization, and applications in wound dressings Ting-Ting Li1,2, Yanqin Zhong1, Hao-Kai Peng1, Hai-Tao Ren1, Hongli Chen3, Jia-Horng Lin1,4,5,*, and Ching-Wen Lou1,6,7,* 1
Innovation Platform of Intelligent and Energy-Saving Textiles, School of Textile Science and Engineering, Tiangong University, Tianjin 300387, China 2 Tianjin and Ministry of Education Key Laboratory for Advanced Textile Composite Materials, Tiangong University, Tianjin 300387, China 3 School of Life Sciences, Tiangong University, Tianjin 300387, China 4 Laboratory of Fiber Application and Manufacturing, Department of Fiber and Composite Materials, Feng Chia University, Taichung 40724, Taiwan 5 School of Chinese Medicine, China Medical University, Taichung 40402, Taiwan 6 Department of Bioinformatics and Medical Engineering, Asia University, Taichung 41354, Taiwan 7 Department of Medical Research, China Medical University Hospital, China Medical University, Taichung 40402, Taiwan
Received: 22 July 2020
ABSTRACT
Accepted: 3 November 2020
The use of regular wound dressings commonly brings about excessively retained wound exudate between the dressing and the wound, which is detrimental to the healing. This study manages to control the biofluid around wounds effectively. To begin with, silk fibroin (SF) is extracted from silk. Next, SF and PCL are mixed and electrospun into multiscale hydrophobic nanofibers on the surface of the dopamine (PDA)-treated hydrophilic PVA nanofibrous membranes, thereby forming asymmetric wetability composite membranes with one-way water conduction. Moreover, PVA nanofibrous membranes are immersed in a PDA solution with an attempt to have a greater surface chemical activity and thus demonstrate an 85% greater wicking height and an air permeability being 90 mm/s. A 20% (w/v) SF solution and an 8% (w/v) PCL solution with a feeding rate being 1:3 provide the resulting SF/PCL nanofibrous membranes with greater hydrophobic properties, namely a water contact angle being 112°. In addition, the ultimate asymmetric wetability composite membranes exhibit an excellent wetting gradient, which benefits the directional transmission of moisture. The moisture management test results indicate that
Published online: 19 November 2020
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Springer Science+Business
Media, LLC, part of Springer Nature 2020
Handling Editor: Annela M. Seddon. Ting-Ting Li and Yanqin Zhong have contributed equally to this work.
Address correspondence to E-mail: [email protected]; [email protected]
https://doi.org/10.1007/s10853-020-05531-4
4408
J Mater Sci (2021) 56:4407–4419
when the electrospinning time for PVA and SF/PCL layers is separately 30 min and 5 min, the resulting composite membranes attain the effect of one-way water conduction. In vitro analysis confirmed that the composite membrane produced were non-toxic. This unique wound dressing with one-way water conduction has a giant potential to serve as new type wound dressings for clinical use.
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