Mycoplasma hyorhinis as a possible cause of fibrinopurulent meningitis in pigs? - a case series
- PDF / 902,606 Bytes
- 8 Pages / 595.276 x 790.866 pts Page_size
- 92 Downloads / 186 Views
(2020) 6:38
CASE REPORT
Open Access
Mycoplasma hyorhinis as a possible cause of fibrinopurulent meningitis in pigs? - a case series Moritz Bünger1, Rene Brunthaler2, Christine Unterweger1, Igor Loncaric3, Maximiliane Dippel1, Ursula Ruczizka1, Lukas Schwarz1, Alfred Griessler4, Thomas Voglmayr4, Doris Verhovsek1,5, Andrea Ladinig1*† and Joachim Spergser3†
Abstract Background: Mycoplasma hyorhinis is an invader of the upper respiratory tract in swine that is considered to have ubiquitous distribution. It is mainly known for causing polyserositis and polyarthritis in weaned piglets, even though the mechanisms of systemic spread are not fully understood. Mycoplasma hyorhinis has also been associated with other diseases in pigs such as pneumonia or otitis media, but so far has not been known to cause central nervous disorders. This case series reports the isolation of Mycoplasma hyorhinis from cerebrospinal fluid and/ or meningeal swabs from piglets originating from four different piglet producing farms in Austria. Case presentation: On farm 1, coughing, stiff movement and central nervous signs occurred in nursery piglets. Mycoplasma hyorhinis was the only pathogen isolated from meningeal swabs from two piglets showing central nervous signs. Fibrinopurulent leptomeningitis was only observed in one piglet. Only one of two nursery piglets from farm 2 showed mild central nervous signs but no histologic lesions; Mycoplasma hyorhinis was isolated from cerebrospinal fluid of the piglet with neurologic signs. Mycoplasma hyorhinis was isolated from cerebrospinal fluid of all three investigated piglets from farm 3, all of which showed central nervous signs and purulent leptomeningitis. Further, Streptococcus suis was isolated from the cerebrospinal fluid of one piglet. Fibrinopurulent leptomeningitis was detected in two piglets from farm 4 that had died overnight without showing any clinical signs and Mycoplasma hyorhinis was isolated from meningeal swabs from both piglets. Conclusion: While causality has yet to be proven by experimental infection and in situ detection of the pathogen in histologic sections, the findings of this study and the absence of other pathogens suggest Mycoplasma hyorhinis as a potential causative agent of meningitis in swine. Keywords: Mycoplasma hyorhinis, Meningitis, Central nervous signs, Nursery piglets
* Correspondence: [email protected] † Andrea Ladinig and Joachim Spergser contributed equally to this work. 1 University Clinic for Swine, Vetmeduni Vienna, Vienna, Austria Full list of author information is available at the end of the article © The Author(s). 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are incl
Data Loading...
