Nucleoside and Nucleotide Transmission in Sensory Systems
Nucleotide and nucleoside signaling occurs via autocrine, paracrine, and neurotransmission modes, mediated by P2 (nucleotide) and P1 (adenosine A1–A3) receptor transduction paths, dynamically linked to purine and pyrimidine release (ATP, associated hydrol
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Purinergic and Pyrimidinergic Signalling I Molecular, Nervous and Urogenitary System Function Contributors M.P. Abbracchio, M. Boarder, G. Burnstock, I.P. Chessell, G.P. Connolly, TY. Dunwiddie, G.D. Housley, P.P.A. Humphrey, K.A. Jacobson, C. Kennedy, LJ.S. Knutsen, A. Lorenzen, S.A. Masino, A.D. Michel, IT Neary, M. Salter, U. Schwabe, A. Sollevi, B. Sperhlgh, E.S. Vizi, TE. Webb, M. Williams, H. Zimmermann
Editors
M.P. Abbracchio and M. Williams
Springer
Professor MARIA PIA ABBRACCHIO
Institute of Pharmacological Sciences University of Milan Via Balzaretti, 9 20133 Milan ITALY e-mail: [email protected]
Dr. MICHAEL \VILLIAMS Department of Molecular Pharmacology and Biological Chemistry Northwestern University Medical School Scarle 8-477 (S-215) 303 East Chicago Avenue Chicago, IL 60611 e-mail: ruerivo\[email protected] With 64 Figures and 21 Tables ISBN 978-3-642-08742-4 ISBN 978-3-662-09604-8 (eBook) DOI 10.1007/978-3-662-09604-8 Library of Congress Cataloging-in-Publication Data Purincrgic and pyrimidinergic signalling I contributors. M.P Abbraechio ... [et al.]: editors. M.P. Abbraeehio and M. Williams. p. cm. - (Handbook of experimental pharmacology: v. 151) Includes bibliographieal referenees and index. Contents: 1. Muscular. nervous. and urogenitary system funetion - 2. Cardiovascular. respiraton'. immune. metabolie. and gastrointestinal tract function.
L Purines - Receptars. 2. Pyrimidines - Reeeptors. 3. Purines - Physiologieal effec!. 4. Pyrimidines - Physiologieal effeet. L Abbracchio. M."- (Maria P). 1956IL Williams. Michael. 1947 Jan, 3. llL Series. QP9115.H3 voL 151 [QPg()LP~J
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00-048277
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© Springer-Verlag Berlin Heidelberg 2001
Originally published by Springer-Verlag Berlin HeideJberg New York in 2001
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Preface
The field of purinergic receptor research has gradually emerged from that of
