Optimization of parameters for femoral component implantation during TKA using finite element analysis and orthogonal ar

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RESEARCH ARTICLE

Open Access

Optimization of parameters for femoral component implantation during TKA using finite element analysis and orthogonal array testing Zhifang Mou1†, Wanpeng Dong2†, Zhen Zhang2, Aohan Wang2, Guanghong Hu3, Bing Wang4 and Yuefu Dong4*

Abstract Background: Individualized and accurate implantation of a femoral component during total knee arthroplasty (TKA) is essential in achieving equal distribution of intra-articular stress and long-term survival of the prosthesis. However, individualized component implantation remains challenging. This study aimed to optimize and individualize the positioning parameters of a femoral component in order to facilitate its accurate implantation. Methods: Using computer-simulated TKA, the positioning parameters of a femoral component were optimized individually by finite element analysis in combination with orthogonal array testing. Flexion angle, valgus angle, and external rotation angle were optimized in order to reduce the peak value of the pressure on the polyethylene liner of the prosthesis. Results: The optimal implantation parameters of the femoral component were as follows: 1° flexion, 5° valgus angle, and 4° external rotation. Under these conditions, the peak value of the pressure on the polyethylene liner surface was minimized to 16.46 MPa. Among the three parameters, the external rotation angle had the greatest effect on the pressure, followed by the valgus angle and the flexion angle. Conclusion: Finite element analysis in combination with orthogonal array testing can optimize the implantation parameters of a femoral component for TKA. This approach would possibly reduce the wear of the polyethylene liner and prolong the survival of the TKA prosthesis, due to its capacity to minimize stress. This technique represents a new method for preoperative optimization of the implantation parameters that can achieve the best possible TKA outcome. Keywords: Total knee arthroplasty (TKA), Prosthesis, Implantation parameter, Optimization, Finite element analysis, Orthogonal array testing

Background Total knee arthroplasty (TKA) is an effective therapy for terminal-stage osteoarthritis of the knee and can ameliorate pain, correct deformity, and improve the function of the joint [1]. Over 90% of implanted prostheses last approximately 10 to 15 years following TKA [2–4]. To date, TKA is a proven technique that is based on * Correspondence: [email protected] † Zhifang Mou and Wanpeng Dong contributed equally to this work. 4 Department of Orthopedics, The Affiliated Lianyungang Hospital of Xuzhou Medical University/the First People’s Hospital of Lianyungang, Lianyungang, China Full list of author information is available at the end of the article

established surgical principles, among which accurate osteotomy and prosthesis implantation are fundamental requirements. TKA aims to restore the neutral mechanical alignment of the lower extremity and promote the uniform distribution of stress in the knee joint, thereby prolonging the survival of the prosthesis by red