Optimized assessment of both left and right ventricular parameters from multi-slice acquisitions of single orientations
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Optimized assessment of both left and right ventricular parameters from multi-slice acquisitions of single orientations using reconstructed 3D cine data Daniel Messroghli1*, Markus Huellebrand2, Darach O h-Ici1, Anja Hennemuth2, Titus Kuehne1 From 15th Annual SCMR Scientific Sessions Orlando, FL, USA. 2-5 February 2012 Background The assessment of global left-ventricular (LV) parameters from a stack of multiple slices is usually performed in short-axis orientation, whereas transversal orientation is commonly preferred for the assessment of right-ventricular (RV) parameters. Other choices carry the risk of inaccuracies due to hindered delineation of valvular planes. The purpose of our study was to reconstruct 3D cine data sets in short-axis orientation from transversal image data and vice versa, and to assess the accuracy of global LV and RV parameters derived from these reconstructed data sets as compared to that from data sets with targeted acquisition in both orientations. Methods In 10 patients with congenital heart disease (age 16 to 46 years, 4 male), multi-slice cine data sets encompassing both ventricles were acquired in both short-axis and transversal orientation (balanced steady-state free precession, 30 phases, slice thickness 6 mm, no inter-slice gap). LV and RV end-diastolic volumes (EDV), end-systolic volumes (ESV), and ejection fraction (EF) were derived from the acquired data sets. Using a custombuilt CMR analysis program (CAIPI), transversal data sets were reconstructed from images acquired in shortaxis orientation, and short-axis data sets were reconstructed from images acquired in transversal orientation. The same biventricular parameters were then derived from the reconstructed data sets using a semi-automatic contour detection tool from CAIPI. 1 Congenital Heart Disease and Pediatric Cardiology, Deutsches Herzzentrum Berlin, Berlin, Germany Full list of author information is available at the end of the article
Results On the acquired data sets, mean differences between ventricular parameters as assessed from short-axis and transversal orientation ranged from 0.4+/-10.4% (RV EF) to 12.3+/-9.7% (RV ESV). Bland-Altman comparison showed better agreement between LV parameters derived from reconstructed short-axis and acquired short-axis data sets than between acquired transversal and acquired short-axis data sets. In concordance, there was higher agreement between RV parameters derived from reconstructed transversal and acquired transversal data sets than between acquired short-axis and transversal data sets. Conclusions The use of reconstructed 3D cine data sets allows for using optimal analysis planes for both ventricles with high diagnostic accuracy and without the need for timeconsuming acquisition of two separate cine data sets. Funding DFG, BMBF. Author details 1 Congenital Heart Disease and Pediatric Cardiology, Deutsches Herzzentrum Berlin, Berlin, Germany. 2Institute for Medical Image Computing, Fraunhofer Mevis, Bremen, Germany. Published: 1 February 2012
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