Pancreaticobiliary Maljunction and Congenital Biliary Dilatation

From embryology to epidemiology, pathophysiology, diagnosis, complications, treatment and prognosis, this book provides a comprehensive overview and the latest evidence-based data on pancreaticobiliary maljunction (PBM), a congenital malformation in which

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Terumi Kamisawa Hisami Ando Editors

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Pancreaticobiliary Maljunction and Congenital Biliary Dilatation

Terumi Kamisawa • Hisami Ando Editors

Pancreaticobiliary Maljunction and Congenital Biliary Dilatation

Editors Terumi Kamisawa Department of Internal Medicine Tokyo Metropolitan Komagome Hospital Bunkyo-ku Tokyo Japan

Hisami Ando Aichi Prefectural Colony Kasugai Aichi Japan

ISBN 978-981-10-8653-3    ISBN 978-981-10-8654-0 (eBook) https://doi.org/10.1007/978-981-10-8654-0 Library of Congress Control Number: 2018941815 © Springer Nature Singapore Pte Ltd. 2018 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This Springer imprint is published by the registered company Springer Nature Singapore Pte Ltd. part of Springer Nature The registered company address is: 152 Beach Road, #21-01/04 Gateway East, Singapore 189721, Singapore

Preface

Pancreaticobiliary maljunction (PBM) is a congenital malformation in which the pancreatic and bile ducts join outside the duodenal wall, usually forming a markedly long common channel. The sphincter of Oddi is normally located at the distal end of the pancreatic and bile ducts and regulates the outflow of bile and pancreatic juice. As the action of the sphincter of Oddi does not functionally affect the pancreaticobiliary junction in PBM, reciprocal reflux between pancreatic juice and bile (pancreaticobiliary reflux and biliopancreatic reflux) occurs, resulting in various pathologic conditions such as biliary cancer and pancreatitis. The fluid pressure in the pancreatic duct usually exceeds that in the bile duct, and reflux of pancreatic juice into the biliary tract frequently occurs. PBM is diagnosed when an abnormally long common channel is evident on imaging studies. PBM is divided into congenital biliary dilatation (CBD) and PBM without biliary dilatation. CBD, the so-called choledochal