Parathyroid Neuroendocrine Neoplasms
The parathyroid glands are the site of common benign neuroendocrine tumors, including adenomas and lipoadenomas. Metastatic disease is very rare, and local growth does not usually have significant sequelae; even large non-metastatic tumors are easily rese
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The Spectrum of Neuroendocrine Neoplasia
Sylvia L. Asa • Stefano La Rosa Ozgur Mete Editors
The Spectrum of Neuroendocrine Neoplasia A Practical Approach to Diagnosis, Classification and Therapy
Editors Sylvia L. Asa University Hospitals Cleveland Medical Center Case Western Reserve University Cleveland, OH USA
Stefano La Rosa Institute of Pathology University Hospital of Lausanne Lausanne, Vaud Switzerland
Ozgur Mete Department of Pathology University Health Network Toronto, ON Canada
ISBN 978-3-030-54390-7 ISBN 978-3-030-54391-4 (eBook) https://doi.org/10.1007/978-3-030-54391-4 © Springer Nature Switzerland AG 2021 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
Preface
Neuroendocrine neoplasms comprise a large family of proliferative lesions that involve almost every part of the body. Our understanding of their cells of origin as well as the pathology, pathophysiology, and genetics of these neoplasms has made tremendous advances in the last few decades. While they are often discussed as separate entities in textbooks of gastroenteropancreatic pathology and pulmonary pathology, their scope is much broader. In this book, we hope to convey the similarities and differences of these fascinating tumors that may be found from the hypothalamus and pituitary to the rectum, and in soft tissue as well as in many organs. We emphasize their structural, functional, predictive, and prognostic features and attempt to provide the clinical context that allows improved diagnosis and therapy, while building on the genetics that clarifies patterns of inheritance and predisposition to tumor development through precursor lesions. We thank our colleagues who contributed to the chapters in t
