Periostin
This book provides a comprehensive and up-to-date review of current understanding of periostin and its importance for human health and disease. Periostin is a secretory matricellular protein that has been revealed to play key roles in fibrillogenesis and
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Akira Kudo Editor
Periostin
Advances in Experimental Medicine and Biology Volume 1132
Editorial Board IRUN R. COHEN, The Weizmann Institute of Science, Rehovot, Israel ABEL LAJTHA, N.S. Kline Institute for Psychiatric Research, Orangeburg, NY, USA JOHN D. LAMBRIS, University of Pennsylvania, Philadelphia, PA, USA RODOLFO PAOLETTI, University of Milan, Milan, Italy NIMA REZAEI, Tehran University of Medical Sciences, Children’s Medical Center Hospital, Tehran, Iran
More information about this series at http://www.springer.com/series/5584
Akira Kudo Editor
Periostin
Editor Akira Kudo International Frontier Tokyo Institute of Technology Tokyo, Japan School of Dentistry Showa University Tokyo, Japan
ISSN 0065-2598 ISSN 2214-8019 (electronic) Advances in Experimental Medicine and Biology ISBN 978-981-13-6656-7 ISBN 978-981-13-6657-4 (eBook) https://doi.org/10.1007/978-981-13-6657-4 © Springer Nature Singapore Pte Ltd. 2019 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Singapore Pte Ltd. The registered company address is: 152 Beach Road, #21-01/04 Gateway East, Singapore 189721, Singapore
Preface
In the middle of 2018, the number of periostin-related publications in PubMed was greater than 1000. This number had been increasing every year by the real significance emerged during the past decade. The majority of publications correspond to incurable diseases related to the heart, cancer, bone, and immune systems. Thus, detailed knowledge of periostin would provide opportunities to cure these diseases. Of these diseases, understanding the contribution of periostin on fibrosis is particularly important, since there are not any effective cures. The entire periostin mechanism is an area of ongoing investigation. However, by reviewing our current understanding of periostin wi
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