Potentially inappropriate drugs increase healthcare use and costs
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PharmacoEconomics & Outcomes News 866, p26 - 14 Nov 2020 Potentially inappropriate drugs increase healthcare use and costs Potentially inappropriate medication (PIM) prescribed to elderly patients in the US increases healthcare use and expenditure, according to findings of a study published in the Journal of the American Geriatrics Society. US Medical Expenditure Panel Survey (MEPS) data from 2011 to 2015 were used to investigate the prevalence of PIM prescribing in community-dwelling adults 65 years of age and over, and associate healthcare utilisation and expenditure. The prevalence of PIM prescribing over the 5-year study period was 34.3%. Prescriptions for the following PIM drugs or drug classes decreased significantly during the study period: antidepressants, antispasmodics, barbiturates, digoxin, androgens, estrogens, non-benzodiazepine hypnosedatives and metoclopramide. PIM prescribing was associated with increase rates of hospitalisation (adjusted incidence rate ratio [aIRR] 1.17; 95% CI 1.08, 1.26), emergency department visits (aIRR 1.26; 95% CI 1.17, 1.35) and outpatient visits (aIRR 1.18; 95% CI 1.14 1.21; all p
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