Prilocaine
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Prilocaine Severe allergic reaction: case report A 60-year-old woman developed a severe allergic reaction to prilocaine during IV regional anaesthesia. The woman was admitted for surgery for carpal tunnel syndrome. IV regional anaesthesia was induced with 10mL of saline plus 0.5% prilocaine 3 mg/kg diluted in saline to a total of 40mL. After 2–3 minutes, she developed severe erythema and oedema at her whole limb below the tourniquet level. The woman received IV hydrocortisone and, 20 minutes later, the tourniquet cuff was deflated; the operation was postponed. Within an hour, her skin symptoms had resolved without any further reactions above the tourniquet level. After 3 weeks, the woman underwent skin prick testing with 0.5% prilocaine with a slight positive reaction. Subsequently, an intradermal injection of 1:100 diluted 0.5% prilocaine elicited an immediate response with a erythematous wheal of 1cm in diameter. Dogramaci Y, et al. Severe allergic reactions to prilocaine during intravenous regional anesthesia. European Journal of Dermatology 18: 462-463, No. 4, Jul-Aug 801111961 2008 - Turkey
0114-9954/10/1211-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved
Reactions 19 Jul 2008 No. 1211
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