Primary malignant pericardial mesothelioma - a rare cause of pericardial effusion and consecutive constrictive pericardi
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Case report
Primary malignant pericardial mesothelioma - a rare cause of pericardial effusion and consecutive constrictive pericarditis: a case report Thomas Butz1,2*, Lothar Faber1, Christoph Langer1, Jan Körfer3, Oliver Lindner3, Andrea Tannapfel4, Klaus-Michael Müller4, Axel Meissner2, Gunnar Plehn2, Hans-Joachim Trappe2, Dieter Horstkotte1 and Cornelia Piper1 Addresses: 1Department of Cardiology, Heart and Diabetes Center North Rhine-Westphalia, Ruhr-University Bochum, D-32545 Bad Oeynhausen, Germany 2 Department of Cardiology and Angiology (Medizinische Klinik II), Marienhospital Herne, Ruhr-University Bochum, D-44627 Herne, Germany 3 Institute of Radiology, Nuclear Medicine and Molecular Imaging, Heart and Diabetes Center North Rhine-Westphalia, Ruhr University Bochum, Bad Oeynhausen, Germany 4 Institute of Pathology, Ruhr-University Bochum, Berufsgenossenschaftliche Universitätsklinik Bergmannsheil (Deutsches Mesotheliomregister), D-44789 Bochum, Germany Email: TB* - [email protected]; LF - [email protected]; CL - [email protected]; JK - [email protected]; OL - [email protected]; AT - [email protected]; KMM - [email protected]; AM - [email protected]; GP - [email protected]; HJT - [email protected]; DH - [email protected]; CP - [email protected] * Corresponding author
Received: 20 December 2008 Accepted: 13 March 2009 Published: 17 September 2009 Journal of Medical Case Reports 2009, 3:9256 doi: 10.4076/1752-1947-3-9256 This article is available from: http://jmedicalcasereports.com/jmedicalcasereports/article/view/9256 © 2009 Butz et al.; licensee Cases Network Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract Introduction: Primary malignant pericardial mesothelioma is a very rare pericardial tumor of unknown etiology. Case presentation: A 61-year-old Caucasian woman was admitted to our hospital complaining of exertional dyspnea due to a large pericardial effusion. Intrapericardial fluid volume declined after repeated pericardiocentesis, but the patient progressively developed a hemodynamically relevant pericardial constriction. Pericardiectomy revealed a pericardial mesothelioma. Subsequently, four cycles of chemotherapy (dosage according to recently published trials) were administered. The patient remained asymptomatic, and there was no recurrence of the tumor after three years. Conclusion: Pericardial mesothelioma should be considered and managed appropriately in nonresponders to pericardiocentesis, and in patients who develop constrictive pericarditis late in their clinical course.
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Journal of Medical Case Reports 2009, 3:9256
http://jmedicalcasereports.com/jmedicalcasereports/article/view/9256
Introduction Primary malignant pericardial mesothelioma is a very rare pericardial tumor of unknown e
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