Primitive Neuroectodermal Tumour (PNET) in subcutaneous abdominal wall: a case report
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BioMed Central
Open Access
Case report
Primitive Neuroectodermal Tumour (PNET) in subcutaneous abdominal wall: a case report Dibendu Betal*1, Behnam Shaygi1, Ramesh Babu1, Kamarul Jamil2 and Richard J Sainsbury1 Address: 1Department of Surgery, St Mary's Hospital, Isle of Wight NHS Trust, Parkhurst Road, Newport, Isle of Wight, PO30 5TG, UK and 2Department of Histopathology, St Mary's Hospital, Isle of Wight NHS Trust, Parkhurst Road, Newport, Isle of Wight, PO30 5TG, UK Email: Dibendu Betal* - [email protected]; Behnam Shaygi - [email protected]; Ramesh Babu - [email protected]; Kamarul Jamil - [email protected]; Richard J Sainsbury - [email protected] * Corresponding author
Published: 31 March 2009 International Seminars in Surgical Oncology 2009, 6:10
doi:10.1186/1477-7800-6-10
Received: 23 December 2008 Accepted: 31 March 2009
This article is available from: http://www.issoonline.com/content/6/1/10 © 2009 Betal et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract Primitive neuroectodermal tumour (PNET) is a rare tumour mainly found in children under ten years old. It may be broadly categorised into those occurring from the central or peripheral nervous system of which the majority arise centrally. We report a 61 year-old lady who had previous lobular breast cancer presenting with a rapidly expanding lesion in her anterior right upper abdominal wall. Clinically it appeared to be benign, however, histopathology of the excised lesion revealed a localised PNET. This case is an unusual case of a PNET in an adult that is peripheral in nature arising from subcutaneous tissue in the abdominal wall.
Background PNETs are rare tumours that are more prevalent in children than adults and occurirng more commonly in the central nervous system than peripheral. Peripheral PNETs are similar to Ewing's sarcoma [1]. We present a case of a peripheral PNET occurring in the subcutaneous abdominal wall.
Case presentation A 61 year-old lady presented to clinic with a lesion in her anterior abdominal wall. It was present for four weeks and initially thought to be a sebaceous cyst but had rapidly expanded in that time frame. She had no other symptoms of note. On clinical examination the patient had a lesion measuring 4 × 3 cm firm, fixed, hemispherical with a smooth edge. There was a punctum and some indurated fat around it.
Her past history was of a right-sided breast cancer, she underwent a wide local excision and axillary dissection for a grade 1 lobular carcinoma with no nodal involvement. She underwent adjuvant treatment with radiotherapy and tamoxifen. She was initially referred due to concern that this lesion was related to her previous breast cancer, however clinically it appeared benign and she underwent elective excision of the
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