Probiotics The scientific basis
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Probiotics The scientific basis Roy Fuller
Springer-Science+Business Media, B. V.
First edition 1992
© 1992 Springer Science+Business Media Dordrecht Originally published by Chapman & Hali in 1992 Softcover reprint of the hardcover Ist edition 1992 Typeset in 10/12 Melior by Falcon Typographic Art Ud, Edinburgh ISBN 978-94-010-5043-2 ISBN 978-94-011-2364-8 (eBook) DOI 10.1007/978-94-011-2364-8 Apart from any fair dealing for the purposes of research or private study, or criticism or review, as permitted under the UK Copyright Designs and Patents Act, 1988, this publication may not be reproduced, stored, or transmitted, in any form or by any means, without the prior permission in writing of the publishers, or in the case of reprographic reproduction only in accordance with the terms of the licences by the Copyright Licensing Agency in the UK, or in accordance with the terms of licences issued by the appropriate Reproduction Rights Organization outside the UK. Enquiries concerning reproduction outside the terms stated here should be sent to the publishers at the London address printed on this page. The publisher makes no representation, express or implied, with regard to the accuracy of the information contained in this book and cannot accept any legal responsibility or liability for any errors or omissions that may be made. A catalogue record for this book is available from the British Library Library of Congress Cataloging-in-Publication data available
Contents
List of contributors Preface Abbreviations used for generic names 1 History and development of probiotics Roy Fuller 1.1 1.2 1.3
Introduction History Composition of probiotic preparations References
2 Bacterial interactions in the gut Pierre Raibaud 2.1 2.2 2.3 2.3
Introduction Methods for studying bacterial interactions Main types of bacterial interactions in the gut Conclusions References
3 Metabolic interactions in the gut Ian R. Rowland 3.1 Introduction 3.2 Mammalian intestinal metabolism 3.3 Gut bacterial metabolism 3.4 Conclusions References
ix xi xii 1 1 1 5
7 9 9 9 11 23 24 29 29 30 32 47 47
vi
Contents
4 Translocation and the indigenous gut flora Rodney D. Berg
Introduction Defence against bacterial translocation Bacterial translocation in animal models with multiple deficiencies in host defences 4.4 Conclusion References 4.1 4.2 4.3
5 Gut flora and disease resistance David J. Hentges
55 55 59 75 76 80 87
5.1 Introduction 87 5.2 Colonization resistance 88 5.3 Suppression of the multiplication of pathogens by the intestinal micro flora 89 5.4 Mechanisms responsible for suppression of pathogens 95 5.5 Conclusions 104 5.6 The probiotic concept 105 References 106 6 Factors affecting the microecology of the gut Rolf Freter
Introduction Definitions Use of one or a limited number of bacterial strains in probiotic preparations 6.4 Ecological considerations 6.5 Recommendations for future developments References 6.1 6.2 6.3
7 Probiotics and the immune state Gabriela Perdig6n and Susana Alvarez
Introduction Effect of orally administere