Protective effects of vitamins (C and E) and melatonin co-administration on hematological and hepatic functions and oxid

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ORIGINAL PAPER

Protective effects of vitamins (C and E) and melatonin co-administration on hematological and hepatic functions and oxidative stress in alloxan-induced diabetic rats Mohamed Salah Allagui & Anouer Feriani & Zouhour Bouoni & Hichem Alimi & Jean Claud Murat & Abdelfattah El Feki Received: 5 December 2013 / Accepted: 3 June 2014 # University of Navarra 2014

Abstract The present study aimed to investigate the potential effects of vitamins (C and E)/melatonin coadministration on the hematologic and hepatic functions and oxidative stress in alloxan-induced diabetic rats. The intraperitoneal injection of alloxan (120 mg/kg b.w. for 2 days) induced a significant increase of blood glucose levels (hyperglycemia) associated with serious hematologic disorders (P

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