Psychosocial Factors and Telomere Length in Peripheral Blood

Telomeres are repetitive DNA sequences that, together with protein complexes, cap and protect eukaryotic chromosomes (Blackburn, FEBS Lett 579:859–862, 2005b). Telomeres are shortened when cells undergo mitosis due to the inability of DNA polymerase to fu

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Jos A. Bosch • Anna C. Phillips • Janet M. Lord Editors

Immunosenescence Psychosocial and Behavioral Determinants

Foreword by Keith W. Kelley, Ph.D.

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Editors Jos A. Bosch University of Amsterdam Amsterdam The Netherlands

Anna C. Phillips University of Birmingham Birmingham United Kingdom

Janet M. Lord University of Birmingham Birmingham United Kingdom

ISBN 978-1-4614-4775-7 ISBN 978-1-4614-4776-4 (eBook) DOI 10.1007/978-1-4614-4776-4 Springer New York Dordrecht Heidelberg London Library of Congress Control Number: 2012952265 © Springer Science+Business Media New York 2013 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. Exempted from this legal reservation are brief excerpts in connection with reviews or scholarly analysis or material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Duplication of this publication or parts thereof is permitted only under the provisions of the Copyright Law of the Publisher’s location, in its current version, and permission for use must always be obtained from Springer. Permissions for use may be obtained through RightsLink at the Copyright Clearance Center. Violations are liable to prosecution under the respective Copyright Law. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. While the advice and information in this book are believed to be true and accurate at the date of publication, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)

Foreword

The post-World War II generation of babies born in the USA between 1946 and 1964 began to reach their 65th birthday earlier this year. This explosion in births, amounting to 76 million American children, temporarily stemmed the tide in the USA’s declining birth rate. Similarly, most western European countries experienced an increase in births immediately following the end of World War II. As these baby boomers join organizations like the American Association of Retired Persons (AARP), they want clearer answers and more effective treatments for their medical ailments. This book, Immunosenescence: Psychosocial and behavioural de