Pulmonary Involvement in Patients with Hematological Malignancies
The number of patients treated for hematological malignancies is increasing steadily. To obtain the highest possible cure rates, aggressive treatments have been introduced, including high-dose chemotherapy, stem cell transplantation, and targeted therapie
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Élie Azoulay (Editor)
Pulmonary Involvement in Patients with Hematological Malignancies
Editor Élie Azoulay, M.D., Ph.D Service de Réanimation Médicale Hôpital Saint-Louis 1 avenue Claude Vellefaux, 75010, Paris France and Medical Intensive Care Units, Saint-Louis Hospital, Paris 7 University, Paris France [email protected]
ISBN 978-3-642-15741-7 e-ISBN 978-3-642-15742-4 DOI 10.1007/978-3-642-15742-4 Springer Heidelberg Dordrecht London New York Library of Congress Control Number: 2011921694 © Springer-Verlag Berlin Heidelberg 2011 This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilm or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright Law of September 9, 1965, in its current version, and permission for use must always be obtained from Springer. Violations are liable to prosecution under the German Copyright Law. The use of general descriptive names, registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Product liability: The publishers cannot guarantee the accuracy of any information about dosage and application contained in this book. In every individual case the user must check such information by consulting the relevant literature. Cover design: eStudioCalamar, Figueres/Berlin Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)
This book is dedicated to all patients: you are the force that drives our work and our most important teachers. Thank you. I would like to dedicate this book to all those who are important to me.
Foreword I
In the United States, cancer is the second most common cause of death. Over 560,000 people die of cancer each year. One in four deaths in the United States is due to cancer. Since the 1970s, the 5-year survival from cancer has increased from 50% to 66%. This improvement in survival reflects earlier diagnosis and more effective therapies and management strategies. As medical technology improves, even more progress is anticipated, but such progress requires experience and analysis, which only highly experienced clinicians and scientists can amass. Patients with hematologic malignancies are a special challenge to health care providers. In the United States, over 130,000 persons are diagnosed with a hematologic malignancy each year, and over 50,000 individuals die. Half of these hematologic malignancies are acute or chronic leukemias, and the remainder is primarily lymphomas or multiple myeloma. These hematologic malignancies represent 9.5% of the cancer burden in the United States. These patients undergo a wide variety of immunosuppressive therapies t
