Rare Kidney Tumors Comprehensive Multidisciplinary Management and Em
This book provides clinicians with clear guidance on treatment decision-making in patients with rare kidney cancers. After a brief review on epidemiology, pathology, and biology, each chapter focuses on the multidisciplinary management of a particular tum
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Rare Kidney Tumors
Gabriel G. Malouf • Nizar M. Tannir Editors
Rare Kidney Tumors Comprehensive Multidisciplinary Management and Emerging Therapies
Editors Gabriel G. Malouf Department of Hematology and Oncology Strasbourg University Hospital Hopital Civil Strasbourg France
Nizar M. Tannir Department of Genitourinary Medical Oncology MD Anderson Cancer Center Houston, Texas USA
ISBN 978-3-319-96988-6 ISBN 978-3-319-96989-3 (eBook) https://doi.org/10.1007/978-3-319-96989-3 Library of Congress Control Number: 2018957321 © Springer Nature Switzerland AG 2019 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
Tannir’s Dedication: “I would like to dedicate this book to my wife Nada and our three children, Zane, Ryan, and Jana, for their love and support; to my mentees and colleagues, Gaby Malouf and Pavlos Msaouel, for enriching my life with their friendship, and for their important contributions to the field of rare kidney tumors; and to our patients for inspiring us and reminding us of the urgency of our research.” Malouf’s Dedication: “I would like to dedicate this book to my mother Chams for her eternal love and infinite support, to the patients and their families, and to my co-editor Nizar Tannir for guiding my first steps in kidney cancer research as well as for his sincere friendship all along the road.”
Preface
In recent years, researchers have made significant progress in the treatment of metastatic clear-cell renal cell carcinoma (ccRCC). Patients with ccRCC now benefit from a range of therapeutic options. However, advances in the treatment of rare, non-clear cell RCC variants have lagged behind those of their more common counterparts. Additionally, it is important to re
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