Regenerative Strategies for the Treatment of Knee Joint Disabilities
This book presents regenerative strategies for the treatment of knee joint disabilities. The book is composed of four main sections totaling 19 chapters which review the current knowledge on the clinical management and preclinical regenerative strat
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Joaquim Miguel Oliveira Rui Luís Reis Editors
Regenerative Strategies for the Treatment of Knee Joint Disabilities
Studies in Mechanobiology, Tissue Engineering and Biomaterials Volume 21
Series editor Amit Gefen, Ramat Aviv, Israel
More information about this series at http://www.springer.com/series/8415
Joaquim Miguel Oliveira Rui Luís Reis Editors
Regenerative Strategies for the Treatment of Knee Joint Disabilities
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Editors Joaquim Miguel Oliveira 3B’s Research Group—Biomaterials, Biodegradables and Biomimetics University of Minho Guimarães Portugal
Rui Luís Reis ICVS/3B’s—PT Government Associate Laboratory University of Minho Guimarães Portugal
ISSN 1868-2006 ISSN 1868-2014 (electronic) Studies in Mechanobiology, Tissue Engineering and Biomaterials ISBN 978-3-319-44783-4 ISBN 978-3-319-44785-8 (eBook) DOI 10.1007/978-3-319-44785-8 Library of Congress Control Number: 2016948273 © Springer International Publishing AG 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
Preface
This book is composed of four main sections totalizing 20 chapters, where the progress on biomaterials and current knowledge on the clinical management and preclinical regenerative strategies for the treatment of knee joint lesions are overviewed. The role of different biomaterials from natural to synthetic, and processing methodologies to obtain scaffolds and patient-specific implants are deeply discussed. The current tissue engineering approaches and bioreactors technology are also revised. The advances on regenerative strategies and future trends based on expert opinion will be highlighted in dedicated chapters. Section one provides an updated and comprehensive discussion on articular cartilage tissue regeneration and role of synovial knee joint. Section two focuse
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