Retrospective analysis of paediatric glaucoma at a tertiary referral centre in Hong Kong
- PDF / 678,368 Bytes
- 7 Pages / 595.276 x 790.866 pts Page_size
- 47 Downloads / 194 Views
CLINICAL INVESTIGATION
Retrospective analysis of paediatric glaucoma at a tertiary referral centre in Hong Kong Jonathan Cheuk‑hung Chan1 · Shing Chuen Chow2 · Jimmy Shiu‑ming Lai1 Received: 22 April 2020 / Accepted: 31 August 2020 © Japanese Ophthalmological Society 2020
Abstract Purpose To evaluate the epidemiological features, clinical interventions, and outcomes of paediatric glaucoma in Hong Kong. Study design Retrospective chart review. Methods Clinical data from the medical records of all patients under 18 years of age diagnosed with glaucoma from January 2008 to December 2017 at a university-affiliated, tertiary referral centre were collected. The patients’ demographics, etiological distribution, clinical interventions, and outcomes were analysed. Results A total of 33 subjects (53 eyes) were identified, 30 (49 eyes) of whom were Chinese. Primary glaucoma accounted for 21.2% of subjects, while 78.8% were diagnosed with secondary glaucoma. The most common subtype was juvenile-onset open angle glaucoma, followed by Sturge-Weber Syndrome related glaucoma. The most commonly performed surgical interventions were tube-shunt surgery (Ahmed Glaucoma Valve) and transscleral cyclophotocoagulation. Most eyes had significant reduction in intraocular pressure after medical or surgical intervention, but deterioration of visual acuity remained common. Conclusion Most cases of childhood glaucoma in Hong Kong are secondary rather than primary, similar to other regions with low incidence of parental consanguinity. The large proportion of secondary glaucoma which generally has poorer prognosis, is reflected by the frequency of multiple surgery, and a high incidence of visual deterioration despite significant intraocular pressure reduction in most eyes. Keywords Childhood glaucoma · Paediatric glaucoma · Epidemiology · Chinese · Hong Kong
Introduction Paediatric glaucoma is a heterogeneous group of eye diseases characterized by impairment of aqueous outflow resulting in a raised intraocular pressure (IOP), which, if left untreated leads to glaucomatous optic neuropathy and eventual blindness [1–3]. Congenital glaucoma accounts for 10.8% of visual impairment in children [4], whereas around 2–6% of all childhood blindness is caused by glaucoma [5]. The proportion of childhood glaucoma resulting in blindness Corresponding Author: Jonathan Chan * Jonathan Cheuk‑hung Chan [email protected]; [email protected] 1
Department of Ophthalmology, LKS Faculty of Medicine, University of Hong Kong, Room 301, Block B, Cyberport 4, Hong Kong, People’s Republic of China
LKS Faculty of Medicine, University of Hong Kong, Hong Kong, People’s Republic of China
2
is even higher in low and middle-income countries [6]. Early diagnosis and effective control of IOP, usually by surgery, is essential for optimizing visual outcomes by preserving useful vision [7, 8]. As paediatric glaucoma is a rare disorder, currently available epidemiological data or studies are scarce [9]. Paediatric glaucoma is classified as primary when elevated IO
Data Loading...
