Rituximab reduces the hospitalization in patients with systemic lupus erythematosus

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POSTER PRESENTATION

Open Access

Rituximab reduces the hospitalization in patients with systemic lupus erythematosus R Martínez-Pérez1*, A Fernández-Nebro2, M López-Lasanta2, M L Velloso-Feijoo1, A Muñoz-Jiménez1, J López Longo3, J L Marenco1 From 5th European Workshop on Immune-Mediated Inflammatory Diseases Sitges-Barcelona, Spain. 1-3 December 2010 Introduction Systemic Lupus Erythematosus (SLE) is a chronic inflammatory disease of unknown etiology. The evolution of the disease is unpredictable. Most patients follow a chronic course and have flare-ups or exacerbations, with a number of hospital admissions.

Table 1 Endpoints Baseline SLEDAI (0–105), median (rank)

24th week

Final Visit

14.5 (7.8-22.3) 4.0 (2.0–6.0)** 2.0 (0.0–4.0)**

PGA (0–3), median (rank)

2.8 (2.0–3.0)

0.0 (0.0–1.0)** 0.0 (0.0-1.0)

Hospitalization, n (%)

25 (54%)

1 (2.3%)**

2 (4%)**

**p