Sickle Cell Disease in Clinical Practice
This practical clinical handbook reveals that sickle cell disease (SCD) is an increasingly common condition to manage in Europe and North America. SCD demands clinical expertise and experience as well as sensitivity to its social and cultural context. Thi
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Jo Howard Paul Telfer
Sickle Cell Disease in Clinical Practice
In Clinical Practice
For further volumes: http://www.springer.com/series/13483
Jo Howard • Paul Telfer
Sickle Cell Disease in Clinical Practice
Jo Howard Department of Haematology Guy’s and St Thomas’ Hospital London UK
Paul Telfer Department of Haematology Royal London Hospital London UK
ISSN 2199-6652 ISSN 2199-6660 (electronic) ISBN 978-1-4471-2472-6 ISBN 978-1-4471-2473-3 (eBook) DOI 10.1007/978-1-4471-2473-3 Springer London Heidelberg New York Dordrecht Library of Congress Control Number: 2014956017 © Springer-Verlag London 2015 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. Exempted from this legal reservation are brief excerpts in connection with reviews or scholarly analysis or material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Duplication of this publication or parts thereof is permitted only under the provisions of the Copyright Law of the Publisher’s location, in its current version, and permission for use must always be obtained from Springer. Permissions for use may be obtained through RightsLink at the Copyright Clearance Center. Violations are liable to prosecution under the respective Copyright Law. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. While the advice and information in this book are believed to be true and accurate at the date of publication, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)
Foreword
Sickle cell disease (SCD) is now one of the most common genetic condition seen in the UK with numbers increasing on an annual basis. In the 1970s, patients were limited almost entirely to London and other large cities, but now there is a reasonable expectation that patients will present with sickle cell crisis and complications in acute hospitals or general practice anywhere in the UK. SCD is an issue also for clinicians practising in almost any specialty, as it is not only a multi-organ condition which may affect the brain, kidneys, eyes or lungs, but in addition, it can complicate the presentation of ot
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