Stress Challenges and Immunity in Space From Mechanisms to Monitorin

This book explains how stress – either psychological or physical – can activate and/or paralyse human innate or adaptive immunity. Adequate immunity is crucial for maintaining health, both on Earth and in space. During space flight, human physiology is sp

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Stress Challenges and Immunity in Space

Alexander Choukér Editor

Stress Challenges and Immunity in Space From Mechanisms to Monitoring and Preventive Strategies Second Edition

Editor Alexander Choukér Laboratory of Translational Research Stress and Immunity Department of Anaesthesiology Hospital of the University of Munich (LMU) Munich Germany

ISBN 978-3-030-16995-4    ISBN 978-3-030-16996-1 (eBook) https://doi.org/10.1007/978-3-030-16996-1 © Springer-Verlag Berlin Heidelberg 2012 © Springer Nature Switzerland AG 2020 Chapters 6, 20 and 28 are Open Access. These chapters are licensed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/). For further details see license information in the chapters. This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland

To my wife Martina To our children Marie-Thérèse, Maxime Amédé, Émile Victor and Alphonse Loïc for support and understanding, for making all possible

Acknowledgments 2nd Edition

The compilation of 40 chapters was only possible with the outstanding support, unending patience and extreme flexibility of the authors to provide, to update and to refine the content in the best possible and feasible way to the overall context. This exchange has been a very rewarding task and all authors in this book deserve my sincerest appreciation for their extremely valuable, professional and always kind collaboration throughout the many iterations of the review process. In science, just as in science related to space and space flight, the emerging topics can only be addressed when a solid “chain of contributors” asks new exciting questions and helps raise funds to enable groundbreaking resea